Clathrin-independent pathways of endocytosis

S Mayor, RG Parton… - Cold Spring Harbor …, 2014 - cshperspectives.cshlp.org
There are many pathways of endocytosis at the cell surface that apparently operate at the
same time. With the advent of new molecular genetic and imaging tools, an understanding of …

Mechanisms of endocytosis

GJ Doherty, HT McMahon - Annual review of biochemistry, 2009 - annualreviews.org
Endocytic mechanisms control the lipid and protein composition of the plasma membrane,
thereby regulating how cells interact with their environments. Here, we review what is known …

Endophilin marks and controls a clathrin-independent endocytic pathway

E Boucrot, APA Ferreira, L Almeida-Souza, S Debard… - Nature, 2015 - nature.com
Endocytosis is required for internalization of micronutrients and turnover of membrane
components. Endophilin has been assigned as a component of clathrin-mediated …

[HTML][HTML] The chemical inhibitors of endocytosis: from mechanisms to potential clinical applications

OK Szewczyk-Roszczenko, P Roszczenko… - Cells, 2023 - mdpi.com
Endocytosis is one of the major ways cells communicate with their environment. This
process is frequently hijacked by pathogens. Endocytosis also participates in the oncogenic …

Endocytosis in the context-dependent regulation of individual and collective cell properties

S Sigismund, L Lanzetti, G Scita… - Nature Reviews Molecular …, 2021 - nature.com
Endocytosis allows cells to transport particles and molecules across the plasma membrane.
In addition, it is involved in the termination of signalling through receptor downmodulation …

Pathways and mechanisms of endocytic recycling

BD Grant, JG Donaldson - Nature reviews Molecular cell biology, 2009 - nature.com
Endocytic recycling is coordinated with endocytic uptake to control the composition of the
plasma membrane. Although much of our understanding of endocytic recycling has come …

Search for inhibitors of endocytosis: Intended specificity and unintended consequences

D Dutta, JG Donaldson - Cellular logistics, 2012 - Taylor & Francis
We discuss here the variety of approaches that have been taken to inhibit different forms of
endocytosis. Typically, both non-specific and specific chemical inhibitors of endocytosis are …

Macropinocytosis: mechanisms and regulation

G Salloum, AR Bresnick, JM Backer - Biochemical Journal, 2023 - portlandpress.com
Macropinocytosis is defined as an actin-dependent but coat-and dynamin-independent
endocytic uptake process, which generates large intracellular vesicles (macropinosomes) …

Endocytosis unplugged: multiple ways to enter the cell

S Kumari, S Mg, S Mayor - Cell research, 2010 - nature.com
Endocytosis occurs at the cell surface and involves internalization of the plasma membrane
(PM) along with its constituent membrane proteins and lipids. Endocytosis is involved in …

Subcellular targeting strategies for drug design and delivery

L Rajendran, HJ Knölker, K Simons - Nature reviews Drug discovery, 2010 - nature.com
Many drug targets are localized to particular subcellular compartments, yet current drug
design strategies are focused on bioavailability and tissue targeting and rarely address drug …