With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …

In recent years, lipid metabolism has garnered significant attention as it provides the
necessary building blocks required to sustain tumor growth and serves as an alternative fuel …

Glucose is a critical component in the proinflammatory response of macrophages (MΦs).
However, the contribution of glucose transporters (GLUTs) and the mechanisms regulating …

To ensure optimal environments for their replication and spread, viruses have evolved to
alter many host cell pathways. In the last decade, metabolomic studies have shown that …

Cancer cells support their growth and proliferation by reprogramming their metabolism in
order to gain access to nutrients. Despite the heterogeneity in genetic mutations that lead to …

Viruses and intracellular bacterial pathogens (IBPs) have in common the need of suitable
host cells for efficient replication and proliferation during infection. In human infections, the …

An accelerated de novo lipogenesis (DNL) flux is a common characteristic of cancer cells
required to sustain a high proliferation rate. The DNL enzyme fatty acid synthase (FASN) is …

When viruses infect cells, they almost invariably cause metabolic changes in the infected
cell as well as in several host cell types that react to the infection. Such metabolic changes …

Natural killer (NK) cells play critical roles in protection against hematological malignancies
but can acquire a dysfunctional state, which limits antitumor immunity. However, the …

Background Infection is one of the main risk factors for cancer. Objectives Epidemiology,
pathogenesis, and disease burden of infection-related cancers were reviewed by infectious …