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AFM-based single molecule techniques: unraveling the amyloid pathogenic species
Background: A wide class of human diseases and neurodegenerative disorders, such as
Alzheimer's disease, is due to the failure of a specific peptide or protein to keep its native …
Alzheimer's disease, is due to the failure of a specific peptide or protein to keep its native …
FiberApp: an open-source software for tracking and analyzing polymers, filaments, biomacromolecules, and fibrous objects
Biological semiflexible polymers and filaments such as collagen, fibronectin, actin,
microtubules, coiled-coil proteins, DNA, siRNA, amyloid fibrils, etc., are ubiquitous in nature …
microtubules, coiled-coil proteins, DNA, siRNA, amyloid fibrils, etc., are ubiquitous in nature …
“Nano‐Fishnet” Structure Making Silk Fibers Tougher
Based on the combined technologies of atomic force microscopy, X‐ray
diffraction/scattering, Fourier transform infrared spectra analysis, etc., it is demonstrated that …
diffraction/scattering, Fourier transform infrared spectra analysis, etc., it is demonstrated that …
Stability of amyloid oligomers
Molecular simulations are now commonly used to complement experimental techniques in
investigating amyloids and their role in human diseases. In this chapter, we will summarize …
investigating amyloids and their role in human diseases. In this chapter, we will summarize …
Structural, Nanomechanical, and Computational Characterization of d,l-Cyclic Peptide Assemblies
The rigid geometry and tunable chemistry of d, l-cyclic peptides makes them an intriguing
building-block for the rational design of nano-and microscale hierarchically structured …
building-block for the rational design of nano-and microscale hierarchically structured …
Nanomechanical properties of SSTSAA microcrystals are dominated by the inter-sheet packing
Amyloid fibrils have been associated with human disease for many decades, but it has also
become apparent that they play a functional, non-disease-related role in eg bacteria and …
become apparent that they play a functional, non-disease-related role in eg bacteria and …
Ultra-confined controllable cyclic peptides as supramolecular biomaterials
The capacity to design molecules capable of orchestrated movements in response to
specific stimuli could yield functional biomaterials suitable for diverse innovative materials …
specific stimuli could yield functional biomaterials suitable for diverse innovative materials …
Micro-and nanoscale hierarchical structure of core–shell protein microgels
Protein nanofibrils were first discovered in the context of misfolding and neurodegenerative
diseases but have recently been found in naturally occurring functional materials including …
diseases but have recently been found in naturally occurring functional materials including …
Amyloid-intercalated graphene oxide membranes for enhanced nanofiltration
AC Lin, F **e, R Chang, N Beaver, C Drewery… - Carbon Trends, 2021 - Elsevier
We report on fast pressure-driven nanofiltration of strong GO membranes intercalated by
protein amyloid fibrils. We investigate the effect of protein amyloid fibril loading on …
protein amyloid fibrils. We investigate the effect of protein amyloid fibril loading on …
Quantitative measurement of the mechanical properties of human antibodies with sub-10-nm resolution in a liquid environment
The nanomechanical properties of single human immunoglobulin G and M antibodies were
measured in a liquid environment using a fast force-volume technique with sub-10-nm …
measured in a liquid environment using a fast force-volume technique with sub-10-nm …