Transcranial alternating current stimulation (tACS) can modulate human neural activity and
behavior. Accordingly, tACS has vast potential for cognitive research and brain disorder …

The brain of modern humans has evolved remarkable computational abilities that enable
higher cognitive functions. These capacities are tightly linked to an increase in the size and …

Self-organizing neural organoids represent a promising in vitro platform with which to model
human development and disease,,,–. However, organoids lack the connectivity that exists in …

The neocortex is disproportionately expanded in human compared with mouse,, both in its
total volume relative to subcortical structures and in the proportion occupied by …

We present a unique, extensive, and open synaptic physiology analysis platform and
dataset. Through its application, we reveal principles that relate cell type to synaptic …

The construction of the human nervous system is a distinctly complex although highly
regulated process. Human tissue inaccessibility has impeded a molecular understanding of …

Elucidating the cellular architecture of the human cerebral cortex is central to understanding
our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA …

Human cortex transcriptomic studies have revealed a hierarchical organization of γ-
aminobutyric acid–producing (GABAergic) neurons from subclasses to a high diversity of …

Human cognitive abilities are generally thought to arise from cortical expansion over the
course of human brain evolution. In addition to increased neuron numbers, this cortical …

The biophysical properties of neurons are the foundation for computation in the brain.
Neuronal size is a key determinant of single neuron input–output features and varies …