Microfluidic fabrication of microparticles for biomedical applications

W Li, L Zhang, X Ge, B Xu, W Zhang, L Qu… - Chemical Society …, 2018 - pubs.rsc.org
Droplet microfluidics offers exquisite control over the flows of multiple fluids in microscale,
enabling fabrication of advanced microparticles with precisely tunable structures and …

Recent advances in droplet microfluidics

Y Ding, PD Howes, AJ deMello - Analytical chemistry, 2019 - ACS Publications
Prominent within this technology set are droplet-based microfluidic systems, 3 in which
passive microfluidic structures are used to rapidly generate and manipulate subnanoliter …

Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics

N Shembekar, C Chaipan, R Utharala, CA Merten - Lab on a Chip, 2016 - pubs.rsc.org
Droplet-based microfluidics enables assays to be carried out at very high throughput (up to
thousands of samples per second) and enables researchers to work with very limited …

Hydrogel droplet microfluidics for high-throughput single molecule/cell analysis

Z Zhu, CJ Yang - Accounts of chemical research, 2017 - ACS Publications
Conspectus Heterogeneity among individual molecules and cells has posed significant
challenges to traditional bulk assays, due to the assumption of average behavior, which …

Recent advances in the use of microfluidic technologies for single cell analysis

TW Murphy, Q Zhang, LB Naler, S Ma, C Lu - Analyst, 2018 - pubs.rsc.org
The inherent heterogeneity in cell populations has become of great interest and importance
as analytical techniques have improved over the past decades. With the advent of …

Biopolymer microparticles prepared by microfluidics for biomedical applications

YK Jo, D Lee - Small, 2020 - Wiley Online Library
Biopolymers are macromolecules that are derived from natural sources and have attractive
properties for a plethora of biomedical applications due to their biocompatibility …

One drop at a time: toward droplet microfluidics as a versatile tool for single-cell analysis

A Rakszewska, J Tel, V Chokkalingam, WTS Huck - NPG Asia Materials, 2014 - nature.com
Miniaturization has been the key driver for many remarkable technological developments in
recent decades. Miniaturization has now also extended into biology, thereby setting the …

Recent advances in applications of droplet microfluidics

WL Chou, PY Lee, CL Yang, WY Huang, YS Lin - Micromachines, 2015 - mdpi.com
Droplet-based microfluidics is a colloidal and interfacial system that has rapidly progressed
in the past decade because of the advantages of low fabrication costs, small sample …

Microfluidic devices for forensic DNA analysis: A review

B Bruijns, A Van Asten, R Tiggelaar, H Gardeniers - Biosensors, 2016 - mdpi.com
Microfluidic devices may offer various advantages for forensic DNA analysis, such as
reduced risk of contamination, shorter analysis time and direct application at the crime …

Sequencing of nucleic acids via barcoding in discrete entities

AR Abate, JR Haliburton, F Lan… - US Patent 11,111,519, 2021 - Google Patents
Microfluidic methods for barcoding nucleic acid target molecules to be analyzed, eg, via
nucleic acid sequencing techniques, are provided. Also provided are microfluidic, droplet …