Dementia is a frequent problem encountered in advanced stages of Parkinson disease (PD).
In recent years, research has focused on the pre-dementia stages of cognitive impairment in …

The efficacy of deep brain stimulation (DBS) for Parkinson disease (PD) is well established
for up to 1 or 2 years, but long-term outcome data are still limited. In this Review, we critically …

Parkinson's disease (PD) is the second most common progressive neurodegenerative
disorder mainly in middle‐elderly population, which represents diverse nonmotor symptoms …

In the long-term, with progression of the illness, Parkinson's disease dementia affects up to
90% of patients with Parkinson's disease. With increasing life expectancy in western …

It has been well established that neuronal loss within the cholinergic nucleus basalis of
Meynert (nbM) correlates with cognitive decline in dementing disorders such as Alzheimer's …

Abstract See Gratwicke and Foltynie (doi: 10.1093/brain/awx333) for a scientific commentary
on this article. Cognitive impairments are a prevalent and disabling non-motor complication …

Brain stimulation techniques can modulate cognitive functions in many neuropsychiatric
diseases. Pilot studies have shown promising effects of brain stimulations on Alzheimer's …

The current nosological concept of α-synucleinopathies characterized by the presence of
Lewy bodies (LBs) includes Parkinson's disease (PD), Parkinson's disease dementia (PDD) …

In recent decades, deep brain stimulation (DBS) has been extensively studied due to its
reversibility and significantly fewer side effects. DBS is mainly a symptomatic therapy, but the …

The default mode network (DMN) mediates self-awareness and introspection, core
components of human consciousness. Therapies to restore consciousness in patients with …