Treatment strategies for cryptococcal infection: challenges, advances and future outlook

KR Iyer, NM Revie, C Fu, N Robbins… - Nature Reviews …, 2021 - nature.com
Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …

[PDF][PDF] The contribution of DNA repair pathways to genome editing and evolution in filamentous pathogens

J Huang, DE Cook - FEMS Microbiology Reviews, 2022 - academic.oup.com
DNA double-strand breaks require repair or risk corrupting the language of life. To ensure
genome integrity and viability, multiple DNA double-strand break repair pathways function in …

[HTML][HTML] What are the 100 most cited fungal genera?

CS Bhunjun, YJ Chen, C Phukhamsakda… - Studies in …, 2024 - ingentaconnect.com
The global diversity of fungi has been estimated between 2 to 11 million species, of which
only about 155 000 have been named. Most fungi are invisible to the unaided eye, but they …

Microbial dynamics between yeasts and acetic acid bacteria in kombucha: Impacts on the chemical composition of the beverage

T Tran, C Grandvalet, F Verdier, A Martin, H Alexandre… - Foods, 2020 - mdpi.com
Kombucha is a traditional low-alcoholic beverage made from sugared tea and transformed
by a complex microbial consortium including yeasts and acetic acid bacteria (AAB). To study …

Phylogenomics of a new fungal phylum reveals multiple waves of reductive evolution across Holomycota

LJ Galindo, P López-García, G Torruella… - Nature …, 2021 - nature.com
Compared to multicellular fungi and unicellular yeasts, unicellular fungi with free-living
flagellated stages (zoospores) remain poorly known and their phylogenetic position is often …

Exploring future applications of the apiculate yeast Hanseniaspora

N van Wyk, J Badura, C von Wallbrunn… - Critical Reviews in …, 2024 - Taylor & Francis
As a metaphor, lemons get a bad rap; however the proverb 'if life gives you lemons, make
lemonade'is often used in a motivational context. The same could be said of Hanseniaspora …

Genomic factors shape carbon and nitrogen metabolic niche breadth across Saccharomycotina yeasts

DA Opulente, AL LaBella, MC Harrison, JF Wolters… - Science, 2024 - science.org
Organisms exhibit extensive variation in ecological niche breadth, from very narrow
(specialists) to very broad (generalists). Two general paradigms have been proposed to …

UV radiation in DNA damage and repair involving DNA-photolyases and cryptochromes

YL Vechtomova, TA Telegina, AA Buglak, MS Kritsky - Biomedicines, 2021 - mdpi.com
Prolonged exposure to ultraviolet radiation on human skin can lead to mutations in DNA,
photoaging, suppression of the immune system, and other damage up to skin cancer …

Genome-scale phylogeny and contrasting modes of genome evolution in the fungal phylum Ascomycota

XX Shen, JL Steenwyk, AL LaBella, DA Opulente… - Science …, 2020 - science.org
Ascomycota, the largest and most well-studied phylum of fungi, contains three subphyla:
Saccharomycotina (budding yeasts), Pezizomycotina (filamentous fungi), and …

5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in Cryptococcus

RB Billmyre, S Applen Clancey, LX Li… - Nature …, 2020 - nature.com
Patients infected with the fungal pathogen Cryptococcus are most effectively treated with a
combination of 5-fluorocytosine (5FC) and amphotericin B. 5FC acts as a prodrug, which is …