Genetic load: genomic estimates and applications in non-model animals

G Bertorelle, F Raffini, M Bosse, C Bortoluzzi… - Nature Reviews …, 2022 - nature.com
Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …

[HTML][HTML] The influence of evolutionary history on human health and disease

ML Benton, A Abraham, AL LaBella, P Abbot… - Nature Reviews …, 2021 - nature.com
Nearly all genetic variants that influence disease risk have human-specific origins; however,
the systems they influence have ancient roots that often trace back to evolutionary events …

Genomic prediction of (mal) adaptation across current and future climatic landscapes

T Capblancq, MC Fitzpatrick, RA Bay… - Annual Review of …, 2020 - annualreviews.org
Signals of local adaptation have been found in many plants and animals, highlighting the
heterogeneity in the distribution of adaptive genetic variation throughout species ranges. In …

Climate change‐mediated temperature extremes and insects: From outbreaks to breakdowns

JA Harvey, R Heinen, R Gols… - Global change …, 2020 - Wiley Online Library
Insects are among the most diverse and widespread animals across the biosphere and are
well‐known for their contributions to ecosystem functioning and services. Recent increases …

Local adaptation: causal agents of selection and adaptive trait divergence

SM Wadgymar, ML DeMarche… - Annual Review of …, 2022 - annualreviews.org
Divergent selection across the landscape can favor the evolution of local adaptation in
populations experiencing contrasting conditions. Local adaptation is widely observed in a …

The net effect of functional traits on fitness

DC Laughlin, JR Gremer, PB Adler, RM Mitchell… - Trends in Ecology & …, 2020 - cell.com
Generalizing the effect of traits on performance across species may be achievable if traits
explain variation in population fitness. However, testing relationships between traits and vital …

Space‐for‐time substitutions in climate change ecology and evolution

RSL Lovell, S Collins, SH Martin, AL Pigot… - Biological …, 2023 - Wiley Online Library
In an epoch of rapid environmental change, understanding and predicting how biodiversity
will respond to a changing climate is an urgent challenge. Since we seldom have sufficient …

Causes of maladaptation

SP Brady, DI Bolnick, AL Angert… - Evolutionary …, 2019 - Wiley Online Library
Evolutionary biologists tend to approach the study of the natural world within a framework of
adaptation, inspired perhaps by the power of natural selection to produce fitness …

Seeing the forest for the trees: Assessing genetic offset predictions from gradient forest

ÁJ Láruson, MC Fitzpatrick, SR Keller… - Evolutionary …, 2022 - Wiley Online Library
Gradient Forest (GF) is a machine learning algorithm designed to analyze spatial patterns of
biodiversity as a function of environmental gradients. An offset measure between the GF …

Context dependence of local adaptation to abiotic and biotic environments: a quantitative and qualitative synthesis

RD Briscoe Runquist, AJ Gorton… - The American …, 2020 - journals.uchicago.edu
Understanding how spatially variable selection shapes adaptation is an area of long-
standing interest in evolutionary ecology. Recent meta-analyses have quantified the extent …