Oxidative stress in autism spectrum disorder—current progress of mechanisms and biomarkers

X Liu, J Lin, H Zhang, NU Khan, J Zhang… - Frontiers in …, 2022‏ - frontiersin.org
Autism spectrum disorder (ASD) is a type of neurodevelopmental disorder that has been
diagnosed in an increasing number of children around the world. Existing data suggest that …

Oxidative stress and regeneration

M Jaganjac, L Milkovic, N Zarkovic… - Free Radical Biology and …, 2022‏ - Elsevier
Regeneration is the process of replacing/restoring a damaged cell/tissue/organ to its full
function and is limited respecting complexity of specific organ structures and the level of …

Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4‐hydroxy‐2‐nonenal

A Ayala, MF Muñoz, S Argüelles - Oxidative medicine and …, 2014‏ - Wiley Online Library
Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …

Docosahexaenoic acid (DHA): An essential nutrient and a nutraceutical for brain health and diseases

GY Sun, A Simonyi, KL Fritsche, DY Chuang… - … and Essential Fatty …, 2018‏ - Elsevier
Docosahexaenoic acid (DHA), a polyunsaturated fatty acid (PUFA) enriched in
phospholipids in the brain and retina, is known to play multi-functional roles in brain health …

[HTML][HTML] Detrimental effects of lipid peroxidation in type 2 diabetes: Exploring the neutralizing influence of antioxidants

SC Shabalala, R Johnson, AK Basson, K Ziqubu… - Antioxidants, 2022‏ - mdpi.com
Lipid peroxidation, including its prominent byproducts such as malondialdehyde (MDA) and
4-hydroxy-2-nonenal (4-HNE), has long been linked with worsened metabolic health in …

[HTML][HTML] Redox changes in obesity, metabolic syndrome, and diabetes

B Korac, A Kalezic, V Pekovic-Vaughan, A Korac… - Redox biology, 2021‏ - Elsevier
Abstract" Life is an instantaneous encounter of circulating matter and flowing energy"(Jean
Giaja, Serbian physiologist), is one of the most elegant definitions not only of life but the …

4-Hydroxy-nonenal—A bioactive lipid peroxidation product

RJ Schaur, W Siems, N Bresgen, PM Eckl - Biomolecules, 2015‏ - mdpi.com
This review on recent research advances of the lipid peroxidation product 4-hydroxy-
nonenal (HNE) has four major topics: I. the formation of HNE in various organs and tissues …

Connecting the “dots”: from free radical lipid autoxidation to cell pathology and disease

MK Foret, R Lincoln, S Do Carmo, AC Cuello… - Chemical …, 2020‏ - ACS Publications
Our understanding of lipid peroxidation in biology and medicine is rapidly evolving, as it is
increasingly implicated in various diseases but also recognized as a key part of normal cell …

[HTML][HTML] A pivotal role of Nrf2 in neurodegenerative disorders: a new way for therapeutic strategies

S Suzen, P Tucci, E Profumo, B Buttari, L Saso - Pharmaceuticals, 2022‏ - mdpi.com
Clinical and preclinical research indicates that neurodegenerative diseases are
characterized by excess levels of oxidative stress (OS) biomarkers and by lower levels of …

NRF2-mediated regulation of lipid pathways in viral infection

K Muzammil, ZS Ghnim, IS Gataa… - Molecular Aspects of …, 2024‏ - Elsevier
The first line of defense against viral infection of the host cell is the cellular lipid membrane,
which is also a crucial first site of contact for viruses. Lipids may sometimes be used as viral …