Role of chondrocytes in cartilage formation, progression of osteoarthritis and cartilage regeneration

H Akkiraju, A Nohe - Journal of developmental biology, 2015 - mdpi.com
Articular cartilage (AC) covers the diarthrodial joints and is responsible for the mechanical
distribution of loads across the joints. The majority of its structure and function is controlled …

Adipose-derived stem cells: Implications in tissue regeneration

W Tsuji, JP Rubin, KG Marra - World journal of stem cells, 2014 - pmc.ncbi.nlm.nih.gov
Adipose-derived stem cells (ASCs) are mesenchymal stem cells (MSCs) that are obtained
from abundant adipose tissue, adherent on plastic culture flasks, can be expanded in vitro …

Chondrogenic differentiation of mesenchymal stem cells: challenges and unfulfilled expectations

RA Somoza, JF Welter, D Correa… - Tissue Engineering Part …, 2014 - liebertpub.com
Articular cartilage repair and regeneration provides a substantial challenge in Regenerative
Medicine because of the high degree of morphological and mechanical complexity intrinsic …

Pericytes. Morphofunction, interactions and pathology in a quiescent and activated mesenchymal cell niche

L Díaz-Flores, R Gutiérrez, JF Madrid… - Histology and …, 2009 - digitum.um.es
We review the morphofunctional characteristics of pericytes and report our observations.
After a brief historical background, we consider the following aspects of pericytes: A) Origin …

Stromal vascular progenitors in adult human adipose tissue

L Zimmerlin, VS Donnenberg, ME Pfeifer… - Cytometry Part A …, 2010 - Wiley Online Library
The in vivo progenitor of culture‐expanded mesenchymal‐like adipose‐derived stem cells
(ADSC) remains elusive, owing in part to the complex organization of stromal cells …

Articular cartilage repair: current needs, methods and research directions

D Correa, SA Lietman - Seminars in cell & developmental biology, 2017 - Elsevier
Articular cartilage is a highly specialized tissue whose remarkable properties of
deformability, resistance to mechanical loading, and low-friction gliding are essential to joint …

Mesenchymal stem cells in the treatment of traumatic articular cartilage defects: a comprehensive review

TD Bornes, AB Adesida, NM Jomha - Arthritis research & therapy, 2014 - Springer
Articular cartilage has a limited capacity to repair following injury. Early intervention is
required to prevent progression of focal traumatic chondral and osteochondral defects to …

CD34+ stromal cells/fibroblasts/fibrocytes/telocytes as a tissue reserve and a principal source of mesenchymal cells. Location, morphology, function and role in …

L Díaz-Flores, R Gutiérrez, MP García, FJ Sáez… - 2014 - digitum.um.es
We review the morphofunctional characteristics of CD34+ stromal fibroblastic/fibrocytic cells
(CD34+ SFCs) and report our observations. We consider the following aspects of CD34+ …

Mesenchymal markers on human adipose stem/progenitor cells

L Zimmerlin, VS Donnenberg, JP Rubin… - Cytometry Part …, 2013 - Wiley Online Library
The stromal‐vascular fraction (SVF) of adipose tissue is a rich source of multipotent stem
cells. We and others have described three major populations of stem/progenitor cells in this …

Infrapatellar fat pad/synovium complex in early-stage knee osteoarthritis: potential new target and source of therapeutic mesenchymal stem/stromal cells

DN Greif, D Kouroupis, CJ Murdock… - … in bioengineering and …, 2020 - frontiersin.org
The infrapatellar fat pad (IFP) has until recently been viewed as a densely vascular and
innervated intracapsular/extrasynovial tissue with biomechanical roles in the anterior …