The what and who of dietary lignans in human health: Special focus on prooxidant and antioxidant effects

S Soleymani, S Habtemariam, R Rahimi… - Trends in Food Science & …, 2020 - Elsevier
Background Lignans are large group of polyphenols that are formed by the coupling of two
coniferyl alcohol residues. Based on their origin, lignans are broadly grouped into plant …

The idiosyncratic efficacy of spironolactone-loaded PLGA nanoparticles against murine intestinal schistosomiasis

WE Abd El Hady, GA El-Emam, NE Saleh… - International Journal …, 2023 - Taylor & Francis
Background Schistosomiasis is a chronic debilitating parasitic disease accompanied with
severe mortality rates. Although praziquantel (PZQ) acts as the sole drug for the …

A tri-stimuli responsive (maghemite/PLGA)/chitosan nanostructure with promising applications in lung cancer

F Fernández-Álvarez, G García-García, JL Arias - Pharmaceutics, 2021 - mdpi.com
A (core/shell)/shell nanostructure (production performance≈ 50%, mean diameter≈ 330
nm) was built using maghemite, PLGA, and chitosan. An extensive characterization proved …

In Vivo and in Silico Trypanocidal Activity Evaluation of (−)‐Cubebin Encapsulated in PLGA Microspheres as Potential Treatment in Acute Phase

NBR Neres, D Montagnini, DS Ferreira… - Chemistry & …, 2021 - Wiley Online Library
In this study, the trypomastigotes of a Y strain of Trypanosoma cruzi were inoculated
intraperitoneally into male BALB/c mice weighing approximately 25 g each, which were …

Neuroprotective potential of lignan-rich fraction of Piper cubeba L. by improving antioxidant capacity in the rat's brain

LP Dwita, MI Iwo, R Mauludin, Elfahmi - Brazilian Journal of Biology, 2022 - SciELO Brasil
Piper cubeba contains various types of lignans. These compounds have been found to have
potential pharmacological activities, one being a neuroprotector through an antioxidant …

Evaluation of lignan-loaded poly(ε-caprolactone) nanoparticles: synthesis, characterization, in vivo and in silico schistosomicidal activity

TC Lima, LG Magalhães, LAL Paula… - Natural Product …, 2022 - Taylor & Francis
Lignan dinitrohinokinin displays important biological activities, which led to the preparation
of its poly-ε-caprolactone nanoparticles. Kinetics analysis revealed initially slow drug …

Nanotechnology: Its Usages in Drug Delivery for the Treatment of Human Parasitic Diseases

P Singh, K Niveria, M Yadav, AK Verma - Natural Product Based Drug …, 2023 - Springer
The occurrence of infectious parasitic disease is the leading driver of mortality worldwide.
Treatment of such parasitic disease is challenging due to the minimal target bioavailability of …

Evaluación in vitro del efecto del material particulado y un potencial tratamiento en dos líneas celulares

M Londoño Berrio - repositorio.unal.edu.co
La interacción de los sistemas biológicos con agentes externos puede representar una
desregulación de la homeóstasis celular al generar procesos tóxicos, por esto se hace …