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Soft materials by design: unconventional polymer networks give extreme properties
Hydrogels are polymer networks infiltrated with water. Many biological hydrogels in animal
bodies such as muscles, heart valves, cartilages, and tendons possess extreme mechanical …
bodies such as muscles, heart valves, cartilages, and tendons possess extreme mechanical …
Recent updates of diagnosis, pathophysiology, and treatment on osteoarthritis of the knee
Osteoarthritis (OA) is a degenerative and chronic joint disease characterized by clinical
symptoms and distortion of joint tissues. It primarily damages joint cartilage, causing pain …
symptoms and distortion of joint tissues. It primarily damages joint cartilage, causing pain …
[HTML][HTML] Articular cartilage and osteochondral tissue engineering techniques: Recent advances and challenges
In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …
several decades, osteochondral defect regeneration remains a challenging issue among …
The heterogeneity of mesenchymal stem cells: an important issue to be addressed in cell therapy
J Li, Z Wu, L Zhao, Y Liu, Y Su, X Gong, F Liu… - Stem cell research & …, 2023 - Springer
With the continuous improvement of human technology, the medical field has gradually
moved from molecular therapy to cellular therapy. As a safe and effective therapeutic tool …
moved from molecular therapy to cellular therapy. As a safe and effective therapeutic tool …
MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity
Mesenchymal stem cell (MSC) exosome was previously shown to be effective in repairing
critical size osteochondral defects in an immunocompetent rat model. Here we investigate …
critical size osteochondral defects in an immunocompetent rat model. Here we investigate …
Cell-laden hydrogels for osteochondral and cartilage tissue engineering
Despite tremendous advances in the field of regenerative medicine, it still remains
challenging to repair the osteochondral interface and full-thickness articular cartilage …
challenging to repair the osteochondral interface and full-thickness articular cartilage …
[HTML][HTML] Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration
Objective Clinical and animal studies have demonstrated the efficacy of mesenchymal stem
cell (MSC) therapies in cartilage repair. As the efficacy of many MSC-based therapies has …
cell (MSC) therapies in cartilage repair. As the efficacy of many MSC-based therapies has …
Advancing biomaterials of human origin for tissue engineering
Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …
devices and in the development of tissue engineering, which seeks to unlock the …
[HTML][HTML] Advances and challenges in stem cell culture
C McKee, GR Chaudhry - Colloids and surfaces B: Biointerfaces, 2017 - Elsevier
Stem cells (SCs) hold great promise for cell therapy, tissue engineering, and regenerative
medicine as well as pharmaceutical and biotechnological applications. They have the …
medicine as well as pharmaceutical and biotechnological applications. They have the …
Click hydrogels, microgels and nanogels: Emerging platforms for drug delivery and tissue engineering
Hydrogels, microgels and nanogels have emerged as versatile and viable platforms for
sustained protein release, targeted drug delivery, and tissue engineering due to excellent …
sustained protein release, targeted drug delivery, and tissue engineering due to excellent …