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Emerging non-viral vectors for gene delivery
C Wang, C Pan, H Yong, F Wang, T Bo, Y Zhao… - Journal of …, 2023 - Springer
Gene therapy holds great promise for treating a multitude of inherited and acquired diseases
by delivering functional genes, comprising DNA or RNA, into targeted cells or tissues to elicit …
by delivering functional genes, comprising DNA or RNA, into targeted cells or tissues to elicit …
Microfluidic formulation of nanoparticles for biomedical applications
Nanomedicine has made significant advances in clinical applications since the late-20th
century, in part due to its distinct advantages in biocompatibility, potency, and novel …
century, in part due to its distinct advantages in biocompatibility, potency, and novel …
[HTML][HTML] Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
Although oral drug delivery is the preferred administration route and has been used for
centuries, modern drug discovery and development pipelines challenge conventional …
centuries, modern drug discovery and development pipelines challenge conventional …
[HTML][HTML] Multifunctionality of cyclodextrin-based polymeric nanoparticulate delivery systems for chemotherapeutics, combination therapy, and theranostics
As cancer being the most difficult disease to treat, different kinds of medications and
therapeutic approaches have been prominently developed by scientists. For certain families …
therapeutic approaches have been prominently developed by scientists. For certain families …
Beyond lipids: exploring advances in polymeric gene delivery in the lipid nanoparticles era
The recent success of gene therapy during the COVID‐19 pandemic has underscored the
importance of effective and safe delivery systems. Complementing lipid‐based delivery …
importance of effective and safe delivery systems. Complementing lipid‐based delivery …
Cyclodextrin based natural nanostructured carbohydrate polymers as effective non-viral siRNA delivery systems for cancer gene therapy
Short interfering RNAs (siRNAs), as small non-coding RNA fragments, are one of the widely
studied RNAi inducers for gene modulations. The reasonably designed siRNA probes …
studied RNAi inducers for gene modulations. The reasonably designed siRNA probes …
Tackling TNF-α in autoinflammatory disorders and autoimmune diseases: from conventional to cutting edge in biologics and RNA-based nanomedicines
Autoinflammatory disorders and autoimmune diseases result from abnormal deviations of
innate and adaptive immunity that heterogeneously affect organs and clinical phenotypes …
innate and adaptive immunity that heterogeneously affect organs and clinical phenotypes …
A review on curcumin-loaded electrospun nanofibers and their application in modern medicine
Herbal drugs are safe and show significantly fewer side effects than their synthetic
counterparts. Curcumin (an active ingredient primarily found in turmeric) shows therapeutic …
counterparts. Curcumin (an active ingredient primarily found in turmeric) shows therapeutic …
Biomaterial‐based gene therapy
Y Yu, Y Gao, L He, B Fang, W Ge, P Yang, Y Ju… - MedComm, 2023 - Wiley Online Library
Gene therapy, a medical approach that involves the correction or replacement of defective
and abnormal genes, plays an essential role in the treatment of complex and refractory …
and abnormal genes, plays an essential role in the treatment of complex and refractory …
Macrocyclic‐Amphiphile‐Based Self‐Assembled Nanoparticles for Ratiometric Delivery of Therapeutic Combinations to Tumors
Combination chemotherapy refers to the use of multiple drugs to treat cancer. In this therapy,
the optimal ratio of the drugs is essential to achieve drug synergism and the desired …
the optimal ratio of the drugs is essential to achieve drug synergism and the desired …