Post-translational protein acetylation: an elegant mechanism for bacteria to dynamically regulate metabolic functions
Post-translational modifications (PTM) decorate proteins to provide functional heterogeneity
to an existing proteome. The large number of known PTMs highlights the many ways that …
to an existing proteome. The large number of known PTMs highlights the many ways that …
Acetate as a potential feedstock for the production of value-added chemicals: metabolism and applications
Acetate is regarded as a promising carbon feedstock in biological production owing to its
possible derivation from C 1 gases such as CO, CO 2 and methane. To best use of acetate …
possible derivation from C 1 gases such as CO, CO 2 and methane. To best use of acetate …
Acetate metabolism and the inhibition of bacterial growth by acetate
During aerobic growth on glucose, Escherichia coli excretes acetate, a mechanism called
“overflow metabolism.” At high concentrations, the secreted acetate inhibits growth. Several …
“overflow metabolism.” At high concentrations, the secreted acetate inhibits growth. Several …
The glyoxylate shunt, 60 years on
SK Dolan, M Welch - Annual review of microbiology, 2018 - annualreviews.org
2017 marks the 60th anniversary of Krebs' seminal paper on the glyoxylate shunt (and
coincidentally, also the 80th anniversary of his discovery of the citric acid cycle). Sixty years …
coincidentally, also the 80th anniversary of his discovery of the citric acid cycle). Sixty years …
Structural basis of response regulator function
R Gao, S Bouillet, AM Stock - Annual review of microbiology, 2019 - annualreviews.org
Response regulators function as the output components of two-component systems, which
couple the sensing of environmental stimuli to adaptive responses. Response regulators …
couple the sensing of environmental stimuli to adaptive responses. Response regulators …
Protein acetylation dynamics in response to carbon overflow in Escherichia coli
In E scherichia coli, acetylation of proteins at lysines depends largely on a non‐enzymatic
acetyl phosphate‐dependent mechanism. To assess the functional significance of this post …
acetyl phosphate‐dependent mechanism. To assess the functional significance of this post …
Regulation, function, and detection of protein acetylation in bacteria
VJ Carabetta, IM Cristea - Journal of bacteriology, 2017 - Am Soc Microbiol
ABSTRACT N ε-Lysine acetylation is now recognized as an abundant posttranslational
modification (PTM) that influences many essential biological pathways. Advancements in …
modification (PTM) that influences many essential biological pathways. Advancements in …
Identification of novel protein lysine acetyltransferases in Escherichia coli
Posttranslational modifications, such as N ε-lysine acetylation, regulate protein function. N ε-
lysine acetylation can occur either nonenzymatically or enzymatically. The nonenzymatic …
lysine acetylation can occur either nonenzymatically or enzymatically. The nonenzymatic …
Mechanisms, detection, and relevance of protein acetylation in prokaryotes
Posttranslational modification of a protein, either alone or in combination with other
modifications, can control properties of that protein, such as enzymatic activity, localization …
modifications, can control properties of that protein, such as enzymatic activity, localization …
Changes in the Acetylome and Succinylome of Bacillus subtilis in Response to Carbon Source
S Kosono, M Tamura, S Suzuki, Y Kawamura… - PloS one, 2015 - journals.plos.org
Lysine residues can be post-translationally modified by various acyl modifications in
bacteria and eukarya. Here, we showed that two major acyl modifications, acetylation and …
bacteria and eukarya. Here, we showed that two major acyl modifications, acetylation and …