Regulation of RNA substrate selectivity of m 6 A demethylase ALKBH5 remains elusive.
Here, we identify RNA-binding motif protein 33 (RBM33) as a previously unrecognized m 6 …

Effective bone regeneration through tissue engineering requires a combination of
osteogenic progenitors, osteoinductive biofactors and biocompatible scaffold materials …

Skin injury is repaired through a multi-phase wound healing process of tissue granulation
and re-epithelialization. Any failure in the healing process may lead to chronic non-healing …

Recombinant adenovirus (rAdV) is a commonly used vector system for gene transfer.
Efficient initial packaging and subsequent production of rAdV remains time-consuming and …

Ovarian cancer is the third most common cancer and the second most common cause of
gynecologic cancer death in women. Its routine clinical management includes surgical …

Ovarian cancer (OC) is one of the most lethal malignancies of the female reproductive
system. OC patients are usually diagnosed at advanced stages due to the lack of early …

Background Excessive hepatic glycogen accumulation benefits tumorigenesis and cancer
cell survival. We previously reported that BMP4 has the strongest ability to promote …

Effective repair of large bone defects through bone tissue engineering (BTE) remains an
unmet clinical challenge. Successful BTE requires optimal and synergistic interactions …

Ecotropic viral integration site 1 (EVI1/MECOM) is frequently upregulated in myeloid
malignancies. Here, we present an Evi1-transgenic mouse model with inducible expression …

Adenovirus (Ad) is a non-enveloped linear double-stranded DNA virus with> 50 serotypes in
humans. Ad vectors have been used as gene delivery vehicles to express transgenes, small …