Adolescence is a particularly vulnerable neurodevelopmental period marked by high rates
of engagement with risky alcohol use. This review summarizes the cognitive and neural …

Drug consumption is driven by a drug's pharmacological effects, which are experienced as
rewarding, and is influenced by genetic, developmental, and psychosocial factors that …

Drug addiction represents a dramatic dysregulation of motivational circuits that is caused by
a combination of exaggerated incentive salience and habit formation, reward deficits and …

Per occasion, alcohol consumption is higher in adolescents than in adults in both humans
and laboratory animals, with changes in the adolescent brain probably contributing to this …

This paper first introduces important conceptual and practical distinctions among three key
terms: substance “use,”“misuse,” and “disorders”(including addiction), and goes on to …

Background Adolescence is a critical biological, psychological, and social developmental
stage involving heightened risk for substance use and associated adverse consequences …

Addiction, the most severe form of substance use disorder, is a chronic brain disorder
molded by strong biosocial factors that has devastating consequences to individuals and to …

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study
(https://abcdstudy. org/) is to establish a national longitudinal cohort of 9 and 10 year olds …

Sex differences may play a critical role in modulating how chronic or heavy alcohol use
impacts the brain to cause the development of alcohol use disorder (AUD). AUD is a …

Binge drinking, commonly defined as consuming five or more standard drinks per occasion
for men and four or more drinks for women, typically begins in adolescence. Adolescents …