Short tandem repeats (STRs) are highly polymorphic sequences throughout the human
genome that are composed of repeated copies of a 1–6-bp motif. Over 1 million variable …

The study of microbial communities has undergone significant advancements, starting from
the initial use of 16S rRNA sequencing to the adoption of shotgun metagenomics. However …

Large-scale genomic initiatives, such as the Earth BioGenome Project, require efficient
methods for eukaryotic genome annotation. Here we present an automatic gene finder …

Bacteria use a wide range of immune pathways to counter phage infection. A subset of these
genes shares homology with components of eukaryotic immune systems, suggesting that …

Gene cloning in repeat-rich polyploid genomes remains challenging. Here, we describe a
strategy for overcoming major bottlenecks in cloning of the powdery mildew resistance gene …

Antarctic krill (Euphausia superba) is Earth's most abundant wild animal, and its enormous
biomass is vital to the Southern Ocean ecosystem. Here, we report a 48.01-Gb chromosome …

Motivation Metagenomic binning methods to reconstruct metagenome-assembled genomes
(MAGs) from environmental samples have been widely used in large-scale metagenomic …

Background Ab initio prediction of splice sites is an essential step in eukaryotic genome
annotation. Recent predictors have exploited Deep Learning algorithms and reliable gene …

Short tandem repeats (STRs) are units of 1–6 bp that repeat in a tandem fashion in DNA.
Along with single nucleotide polymorphisms and large structural variations, they are among …

Pseudomonas aeruginosa is an important pathogen that causes chronic infections that
involve multicellular aggregates called biofilms. Within biofilms, bacteria are surrounded in a …