The continuous improvement in cancer care over the past decade has led to a gradual
decrease in cancer-related deaths. This is largely attributed to improved treatment and …

Background It has been hypothesised that manipulation during surgery releases tumoral
components into circulation. We investigate the effect of surgery on plasma-borne DNA …

Background Liquid biopsy based on cell-free DNA (cfDNA) analysis holds significant
promise as a minimally invasive approach for the diagnosis, genoty**, and monitoring of …

Minimal Residual Disease (MRD) detection has emerged as an independent factor in
clinical and pathological cancer assessment offering a highly effective method for predicting …

Gastrointestinal (GI) cancers account for one-fourth of the global cancer incidence and are
incriminated to cause one-third of cancer-related deaths. GI cancer includes esophageal …

Since colon cancer has a high rate of shedding of tumour fragments into the blood, several
research efforts are now focused on the investigation of the minimal residual disease …

Background: While detection of circulating tumor DNA (ctDNA) weeks after surgery is linked
to recurrence for other solid tumors, the optimal time point for ctDNA assessment as a …

Background Right-sided colon cancer (RCC) differs in mutation profile and risk of recurrence
compared to distal colon cancer. Circulating tumour DNA (ctDNA) present after surgery can …

Although the 5-year relative survival rates for resectable solid tumors have improved over
the past few years, the risk of postoperative recurrence necessitates effective monitoring …

Introduction Personalized and tumor-informed circulating tumor DNA (ctDNA) testing is
feasible and allows for molecular residual disease (MRD) identification in patients with …