Biological entities are involved in intricate and complex interactions, in which uncovering the
biological information from the network concepts are of great significance. Benefiting from …

During drug development, safety is always the most important issue, including a variety of
toxicities and adverse drug effects, which should be evaluated in preclinical and clinical trial …

Without foreknowledge of the complete drug target information, development of promising
and affordable approaches for effective treatment of human diseases is challenging. Here …

The recent appearance of COVID-19 virus has created a global crisis due to unavailability of
any vaccine or drug that can effectively and deterministically work against it. Naturally …

In medicine research, drug discovery aims to develop a drug to patients who will benefit from
it and try to avoid some side effects. However, the tradition experiment is time consuming …

Drug-target interaction (DTI) is the basis of drug discovery. However, it is time-consuming
and costly to determine DTIs experimentally. Over the past decade, various computational …

Abstract Objective Drug–drug interactions (DDIs) are an important consideration in both
drug development and clinical application, especially for co-administered medications …

Therapeutic activities of drugs are often influenced by co-administration of drugs that may
cause inevitable drug-drug interactions (DDIs) and inadvertent side effects. Prediction and …

In recent years the amount of experimental data that is produced in biomedical research and
the number of papers that are being published in this field have grown rapidly. In order to …

Background Predicting drug side effects is an important topic in the drug discovery. Although
several machine learning methods have been proposed to predict side effects, there is still …