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[HTML][HTML] Development of novel anti-leishmanials: the case for structure-based approaches
M Soni, JV Pratap - Pathogens, 2022 - mdpi.com
The neglected tropical disease (NTD) leishmaniasis is the collective name given to a diverse
group of illnesses caused by~ 20 species belonging to the genus Leishmania, a majority of …
group of illnesses caused by~ 20 species belonging to the genus Leishmania, a majority of …
A survey for predicting enzyme family classes using machine learning methods
Enzymes are proteins that act as biological catalysts to speed up cellular biochemical
processes. According to their main Enzyme Commission (EC) numbers, enzymes are …
processes. According to their main Enzyme Commission (EC) numbers, enzymes are …
iACP-GAEnsC: Evolutionary genetic algorithm based ensemble classification of anticancer peptides by utilizing hybrid feature space
Cancer is a fatal disease, responsible for one-quarter of all deaths in developed countries.
Traditional anticancer therapies such as, chemotherapy and radiation, are highly expensive …
Traditional anticancer therapies such as, chemotherapy and radiation, are highly expensive …
Computer-aided nanotoxicology: assessing cytotoxicity of nanoparticles under diverse experimental conditions by using a novel QSTR-perturbation approach
Nowadays, the interest in the search for new nanomaterials with improved electrical, optical,
catalytic and biological properties has increased. Despite the potential benefits that can be …
catalytic and biological properties has increased. Despite the potential benefits that can be …
[HTML][HTML] Computational ecotoxicology: Simultaneous prediction of ecotoxic effects of nanoparticles under different experimental conditions
VV Kleandrova, F Luan, H González-Díaz… - Environment …, 2014 - Elsevier
Nanotechnology has brought great advances to many fields of modern science. A manifold
of applications of nanoparticles have been found due to their interesting optical, electrical …
of applications of nanoparticles have been found due to their interesting optical, electrical …
Multi-Endpoint Acute Toxicity Assessment of Organic Compounds Using Large-Scale Machine Learning Modeling
In recent years, alternative animal testing methods such as computational and machine
learning approaches have become increasingly crucial for toxicity testing. However, the …
learning approaches have become increasingly crucial for toxicity testing. However, the …
2D-MH: A web-server for generating graphic representation of protein sequences based on the physicochemical properties of their constituent amino acids
Introduction of graphic representation for biological sequences can provide intuitive overall
pictures as well as useful insights for performing large-scale analysis. Here, a new two …
pictures as well as useful insights for performing large-scale analysis. Here, a new two …
PredictEFC: a fast and efficient multi-label classifier for predicting enzyme family classes
L Chen, C Zhang, J Xu - BMC bioinformatics, 2024 - Springer
Background Enzymes play an irreplaceable and important role in maintaining the lives of
living organisms. The Enzyme Commission (EC) number of an enzyme indicates its …
living organisms. The Enzyme Commission (EC) number of an enzyme indicates its …
MIND-BEST: Web Server for Drugs and Target Discovery; Design, Synthesis, and Assay of MAO-B Inhibitors and Theoretical− Experimental Study of G3PDH Protein …
Many drugs with very different affinity to a large number of receptors are described. Thus, in
this work, we selected drug− target pairs (DTPs/nDTPs) of drugs with high affinity/nonaffinity …
this work, we selected drug− target pairs (DTPs/nDTPs) of drugs with high affinity/nonaffinity …
PTML model of enzyme subclasses for mining the proteome of biofuel producing microorganisms
Predicting enzyme function and enzyme subclasses is always a key objective in fields such
as biotechnology, biochemistry, medicinal chemistry, physiology, and so on. The Protein …
as biotechnology, biochemistry, medicinal chemistry, physiology, and so on. The Protein …