Autophagy refers to the formation of autophagosomes by membrane wrap** part of the
cytoplasm and the organelles and proteins that need to be degraded in the cells …

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two diseases
that form a broad neurodegenerative continuum. Considerable effort has been made to …

The pathogenesis of acute and chronic pancreatitis has recently evolved as new findings
demonstrate a complex mechanism operating through various pathways. In this review, the …

Endoplasmic reticulum (ER)-associated degradation (ERAD) is the main mechanism of
targeting ER proteins for degradation to maintain homeostasis, and perturbations of ERAD …

Acute pancreatitis (AP) is a common disorder with significant hospital admission and
mortality. Due to the unclarified pathological mechanism, there is still no effective and …

In this report, we describe the architecture of Lipofectamine 2000 and 3000 transfection-
reagents, as they appear inside of transfected cells, using classical transmission electron …

Autophagy is a fundamental mechanism within cells and is crucial in maintaining cellular
homeostasis by eliminating impaired organelles and toxic unfolded proteins. This process …

In this last Editorial for volume 152 (as well as for 2019), we are pleased to once again
highlight three Original Papers. We would also like to introduce a new year end feature, a …

This book chapter explores the complex relationship between autophagy and extracellular
nanovesicles in the context of neurodegenerative disorders. Autophagy, a cellular process …

Autophagy is a set of highly conserved eukaryotic lysosomal degradation pathways of
diverse cytoplasmic components ranging from unfolded proteins and protein aggregates to …