Lipid disorders involving derangements in serum cholesterol, triglycerides, or both are
commonly encountered in clinical practice and often have implications for cardiovascular …

Hypertriglyceridemia (triglycerides 200–499 mg/dL) is relatively common in the United
States, whereas more severe triglyceride elevations (very high triglycerides,≥ 500 mg/dL) …

Importance Severe hypertriglyceridemia (sHTG) confers increased risk of atherosclerotic
cardiovascular disease (ASCVD), nonalcoholic steatohepatitis, and acute pancreatitis …

Pegozafermin, a long-acting glycopegylated analog of human fibroblast growth factor 21, is
in development for the treatment of severe hypertriglyceridemia (SHTG) and nonalcoholic …

Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of death
worldwide. Low-density lipoprotein cholesterol (LDL-C) is a well-established mediator of …

The treatment of lipid disorders begins with lifestyle therapy to improve nutrition, physical
activity, weight, and other factors that affect lipids. Secondary causes of lipid disorders …

Hypertriglyceridemia is the third most common cause of acute pancreatitis. It typically occurs
in patients with an underlying disorder of lipoprotein metabolism and in the presence of a …

Different lifestyles have an impact on useful metabolic functions, causing disorders. Different
lipids are involved in the metabolic functions that play various vital roles in the body, such as …

Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …