An overview of benzo [b] thiophene-based medicinal chemistry

RS Keri, K Chand, S Budagumpi, SB Somappa… - European journal of …, 2017 - Elsevier
Among sulfur containing heterocycles, benzothiophene and its derivatives are at the focus
as these candidates have structural similarities with active compounds to develop new …

Hydrazone-based switches, metallo-assemblies and sensors

X Su, I Aprahamian - Chemical Society Reviews, 2014 - pubs.rsc.org
The hydrazone functional group has been extensively studied and used in the context of
supramolecular chemistry. Its pervasiveness and versatility can be attributed to its ease of …

Synthetic plant defense elicitors

Y Bektas, T Eulgem - Frontiers in plant science, 2015 - frontiersin.org
To defend themselves against invading pathogens plants utilize a complex regulatory
network that coordinates extensive transcriptional and metabolic reprogramming. Although …

Biological activities of hydrazone derivatives

S Rollas, Ş Güniz Küçükgüzel - Molecules, 2007 - mdpi.com
There has been considerable interest in the development of novel compounds with
anticonvulsant, antidepressant, analgesic, antiinflammatory, antiplatelet, anti-malarial …

Hydrazide-hydrazone/hydrazone as enabling linkers in anti-cancer drug discovery: A comprehensive review

S Murugappan, S Dastari, K Jungare, NM Barve… - Journal of Molecular …, 2024 - Elsevier
The burgeoning demand for novel cytotoxic drugs possessing improved bioavailability and
safety profiles has spurred the hybridization of various pharmacophores in the past decades …

Acid hydrazides, potent reagents for synthesis of oxygen-, nitrogen-, and/or sulfur-containing heterocyclic rings

P Majumdar, A Pati, M Patra, RK Behera… - Chemical …, 2014 - ACS Publications
Heterocycles form by far the largest of the classical divisions of organic chemistry. Moreover,
they are of immense importance not only both biologically and industrially but also to the …

Synthesis, characterization, and comprehensive computational analysis of aromatic hydrazone compounds: Unveiling quantum parameters, evaluating antioxidant …

YI Touahria, N Chafai, O Moumeni, A Boublia… - Journal of Molecular …, 2024 - Elsevier
This study presents a synergistic approach encompassing experimental synthesis,
computational analysis, and antioxidant activity evaluation of two aromatic hydrazone …

[HTML][HTML] Biological activities of Schiff bases and their complexes: a review of recent works

W Al Zoubi - International Journal of Organic Chemistry, 2013 - scirp.org
Schiff bases are the most widely used organic compounds. They have been shown to exhibit
a broad range of biological activities, including antifungal, antibacterial, antimalarial …

Synthesis and biological evaluation of benzo [d] isothiazole, benzothiazole and thiazole Schiff bases

P Vicini, A Geronikaki, M Incerti, B Busonera… - Bioorganic & medicinal …, 2003 - Elsevier
Three new series of benzo [d] isothiazole, benzothiazole and thiazole Schiff bases were
synthesized and tested in vitro with the aim of identifying novel lead compounds active …

Synthesis and antimicrobial activity of novel 2-thiazolylimino-5-arylidene-4-thiazolidinones

P Vicini, A Geronikaki, K Anastasia, M Incerti… - Bioorganic & medicinal …, 2006 - Elsevier
New 2-thiazolylimino-5-arylidene-4-thiazolidinones (compounds 4a–j), unsubstituted or
carrying hydroxy, methoxy, nitro and chloro groups on the benzene ring, were synthesized …