Fatty acid synthesis promotes inflammasome activation through NLRP3 palmitoylation
S Leishman, NM Aljadeed, L Qian, S Cockcroft… - Cell Reports, 2024 - cell.com
Despite its significance, the role of lipid metabolism in NLRP3 inflammasome remains
elusive. Here, we reveal a critical role for fatty acid synthase (FASN) in NLRP3 …
elusive. Here, we reveal a critical role for fatty acid synthase (FASN) in NLRP3 …
[HTML][HTML] Plasma and platelet lipidome changes in Fabry disease
B Burla, J Oh, A Nowak, N Piraud, E Meyer, D Mei… - Clinica Chimica …, 2024 - Elsevier
Background Fabry disease (FD) is an X-linked lysosomal storage disorder characterized by
the progressive accumulation of globotriaosylceramide (Gb3) leading to systemic …
the progressive accumulation of globotriaosylceramide (Gb3) leading to systemic …
1, 5-AG suppresses pro-inflammatory polarization of macrophages and promotes the survival of B-ALL in vitro by upregulating CXCL14
M Wu, S Zhang, C Chi, H Zhu, H Ma, L Liu, Q Shi… - Molecular …, 2023 - Elsevier
B-lineage acute lymphoblastic leukemia (B-ALL) is one of the most common malignancies in
children. Despite advances in treatment, the role of the tumor microenvironment in B-ALL …
children. Despite advances in treatment, the role of the tumor microenvironment in B-ALL …
Neutral Sphingomyelinase 2 Inhibition Limits Hepatic Steatosis and Inflammation
Non-alcoholic fatty liver disease (NAFLD) is manifested by hepatic steatosis, insulin
resistance, hepatocyte death, and systemic inflammation. Obesity induces steatosis and …
resistance, hepatocyte death, and systemic inflammation. Obesity induces steatosis and …
Helminth-derived metabolites induce tolerogenic functional, metabolic, and transcriptional signatures in dendritic cells that attenuate experimental colitis
NL Malacco, AN Michi, E Siciliani, AG Madrigal… - bioRxiv, 2023 - biorxiv.org
Inflammatory bowel diseases (IBD) are chronic inflammatory diseases in which abdominal
pain, bloody diarrhea, weight loss, and fatigue collectively result in diminished quality of …
pain, bloody diarrhea, weight loss, and fatigue collectively result in diminished quality of …
Helminth Infection Modulation of Antigen-Induced-Arthritis: Characterizing the Effects of Heligmosomoides Polygyrus Bakeri Infection on Murine Knee Joint …
AG Madrigal - 2022 - search.proquest.com
Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease and is a
leading cause of disability worldwide. RA affects 0.5–1% of the world population, affecting …
leading cause of disability worldwide. RA affects 0.5–1% of the world population, affecting …
Helminth infection modulation of AIA: Characterizing the effects of «Heligmosomoides polygyrus bakeri» infection on knee joint inflammation
A Madrigal - 2023 - escholarship.mcgill.ca
La polyarthrite rhumatoïde (PR) est la maladie articulaire inflammatoire chronique la plus
courante et l'une des principales causes d'invalidité dans le monde. La PR touche 0, 5 à 1 …
courante et l'une des principales causes d'invalidité dans le monde. La PR touche 0, 5 à 1 …
慢性子宮內膜炎致炎机制的研究进展.
熊玉晶， 罗婉彬， 艾细雄… - Journal of International …, 2023 - search.ebscohost.com
慢性子宫内膜炎(chronic endometritis, CE) 是病原体感染所致的慢性子宫内膜炎性疾病,
与不良妊娠结局密切相关. 目前关于CE 的诊断和治疗尚不统一, 研究CE 的致炎机制有助于完善 …
与不良妊娠结局密切相关. 目前关于CE 的诊断和治疗尚不统一, 研究CE 的致炎机制有助于完善 …