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Frontotemporal dementia, where do we stand? A narrative review
A Antonioni, EM Raho, P Lopriore, AP Pace… - International journal of …, 2023 - mdpi.com
Frontotemporal dementia (FTD) is a neurodegenerative disease of growing interest, since it
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …
Nanoparticle-based drug delivery systems: an inspiring therapeutic strategy for neurodegenerative diseases
L Duan, X Li, R Ji, Z Hao, M Kong, X Wen, F Guan… - Polymers, 2023 - mdpi.com
Neurodegenerative diseases are common, incurable neurological disorders with high
prevalence, and lead to memory, movement, language, and intelligence impairments …
prevalence, and lead to memory, movement, language, and intelligence impairments …
Progranulin AAV gene therapy for frontotemporal dementia: translational studies and phase 1/2 trial interim results
J Sevigny, O Uspenskaya, LD Heckman, LC Wong… - Nature Medicine, 2024 - nature.com
GRN mutations cause progranulin haploinsufficiency, which eventually leads to
frontotemporal dementia (FTD-GRN). PR006 is an investigational gene therapy delivering …
frontotemporal dementia (FTD-GRN). PR006 is an investigational gene therapy delivering …
The Miami Framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology
M Benatar, J Wuu, ED Huey, CT McMillan… - Nature Reviews …, 2024 - nature.com
Increasing appreciation of the phenotypic and biological overlap between amyotrophic
lateral sclerosis (ALS) and frontotemporal dementia, alongside evolving biomarker evidence …
lateral sclerosis (ALS) and frontotemporal dementia, alongside evolving biomarker evidence …
[HTML][HTML] Unraveling the impact of Omega-3 polyunsaturated fatty acids on blood-brain barrier (BBB) integrity and glymphatic function
J Wen, SK Satyanarayanan, A Li, L Yan, Z Zhao… - Brain, Behavior, and …, 2024 - Elsevier
Alzheimer's disease (AD) and other forms of dementia represent major public health
challenges but effective therapeutic options are limited. Pathological brain aging is …
challenges but effective therapeutic options are limited. Pathological brain aging is …
Alzheimer's disease early diagnostic and staging biomarkers revealed by large-scale cerebrospinal fluid and serum proteomic profiling
QQ Tao, X Cai, YY Xue, W Ge, L Yue, XY Li, RR Lin… - The Innovation, 2024 - cell.com
Amyloid-β, tau pathology, and biomarkers of neurodegeneration make up the core
diagnostic biomarkers of Alzheimer disease (AD). However, these proteins represent only a …
diagnostic biomarkers of Alzheimer disease (AD). However, these proteins represent only a …
A survey of deep learning for Alzheimer's disease
Alzheimer's and related diseases are significant health issues of this era. The
interdisciplinary use of deep learning in this field has shown great promise and gathered …
interdisciplinary use of deep learning in this field has shown great promise and gathered …
[HTML][HTML] The gut microbiome–brain crosstalk in neurodegenerative diseases
L Ghezzi, C Cantoni, E Rotondo, D Galimberti - Biomedicines, 2022 - mdpi.com
The gut–brain axis (GBA) is a complex interactive network linking the gut to the brain. It
involves the bidirectional communication between the gastrointestinal and the central …
involves the bidirectional communication between the gastrointestinal and the central …
Amyloid and tau positron emission tomography imaging in Alzheimer's disease and other tauopathies
The detection and staging of Alzheimer's disease (AD) using non-invasive imaging
biomarkers is of substantial clinical importance. Positron emission tomography (PET) …
biomarkers is of substantial clinical importance. Positron emission tomography (PET) …
Tau in neurodegenerative diseases: molecular mechanisms, biomarkers, and therapeutic strategies
The deposition of abnormal tau protein is characteristic of Alzheimer's disease (AD) and a
class of neurodegenerative diseases called tauopathies. Physiologically, tau maintains an …
class of neurodegenerative diseases called tauopathies. Physiologically, tau maintains an …