The development of therapeutic approaches for the induction of robust, long-lasting and
antigen-specific immune tolerance remains an important unmet clinical need for the …

The central nervous system (CNS) is vulnerable to pathologic processes that lead to the
development of neurodegenerative disorders like Alzheimer's, Parkinson's and Huntington's …

Multiple sclerosis (MS) is characterized by chronic inflammatory response-induced
demyelination of the neurons and degeneration of the axons within the central nervous …

Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disease with
unknown etiology that can be characterized by the presence of demyelinated lesions …

Autoimmune disorders are characterized by aberrant T cell and B cell reactivity to the body's
own components, resulting in tissue destruction and organ dysfunction. Autoimmune …

The blood–brain barrier (BBB) is a tailored system of capillary endothelial cells intermixed
with tight junctions and adherent junctions that regulates the transport of various materials …

Aim: Based on the ability of apoptosis to induce immunological tolerance, liposomes were
generated mimicking apoptotic cells, and they arrest autoimmunity in Type 1 diabetes. Our …

Antigen-specific tolerance induction aims at treating multiple sclerosis (MS) at the root of its
pathogenesis and has the prospect of personalization. Several promising tolerization …

Autoimmune diseases affect many people worldwide. Current treatment modalities focus on
the reduction of disease symptoms using anti-inflammatory drugs which can lead to side …

Multiple sclerosis (MS) as a chronic inflammatory disorder of the central nervous system
(CNS) is thought to be caused by the abnormal induction of immune responses …