Infectious diseases, including the coronavirus disease 2019 (COVID-19) pandemic that has
brought the world to a standstill, are emerging at an unprecedented rate with a substantial …

In the growing field of tissue engineering, providing cells in biomaterials with the adequate
biological cues represents an increasingly important challenge. Yet, biomaterials with …

Activated B-cell-like diffuse large B-cell lymphomas (ABC-DLBCLs) are characterized by
constitutive activation of nuclear factor κB driven by the B-cell receptor (BCR) and Toll-like …

Following treatment with androgen receptor (AR) pathway inhibitors,≈ 20% of prostate
cancer patients progress by shedding their AR‐dependence. These tumors undergo …

New discoveries in drugs and drug delivery systems are focused on identifying and
delivering a pharmacologically effective agent, potentially targeting a specific molecular …

Organs-on-chip are gaining increasing attention as promising platforms for drug screening
and testing applications. However, lymph nodes-on-chip options remain limited although the …

Recent developments in organoid culture technologies have made it possible to closely
recapitulate intrinsic characteristics of different tissues under in vitro conditions. These …

Glycoengineered bacteria have emerged as a cost-effective platform for rapid and
controllable biosynthesis of designer conjugate vaccines. However, little is known about the …

Human organoids mimic the physiology and tissue architecture of organs and are of great
significance for promoting the study of human diseases. Traditionally, organoid cultures rely …

MALT1 inhibitors are promising therapeutic agents for B-cell lymphomas that are dependent
on constitutive or aberrant signaling pathways. However, a potential limitation for signal …