Depression is a syndrome of stress-and emotion-dysregulation, involving compromised
structural integrity of frontal-limbic networks. Meta-analytic evidence indicates that volumetric …

There is increasing interest in factors that may modulate white matter (WM) breakdown and,
consequentially, age-related cognitive and behavioral deficits. Recent diffusion tensor …

Executive function declines with age, but engaging in aerobic exercise may attenuate
decline. One mechanism by which aerobic exercise may preserve executive function is …

Introduction Repetitive head impacts (RHI) sustained in contact sports are thought to be
necessary for the long-term development of chronic traumatic encephalopathy (CTE). Our …

White matter structure declines with advancing age and has been associated with a decline
in memory and executive processes in older adulthood. Yet, recent research suggests that …

Articles were identified through Pubmed searches using these terms: DTI, diffusion, WM
microstructural damage, WM integrity, structural network, brain connectivity AND each of the …

Objective: To examine whether structural network connectivity at baseline predicts incident
all-cause dementia in a prospective hospital-based cohort of elderly participants with MRI …

This study used path analysis to examine effects of cognitive activity and physical activity on
cognitive functioning in older adults, through pathways involving beta-amyloid (Aβ) burden …

Competitive sport participation, in contact and collision sports, exposes athletes to repetitive
head impacts. Although these impacts do not always result in overt symptomology or a …

Background Recent epidemiological evidence suggests that modifying lifestyle by
increasing physical activity could be a non-pharmacological approach to improving …