[HTML][HTML] Flavonoids as promising molecules in the cancer therapy: An insight
Cancer continues to increase global morbidity and mortality rates. Despite substantial
progress in the development of various chemically synthesized anti-cancer drugs, the poor …
progress in the development of various chemically synthesized anti-cancer drugs, the poor …
Targeting the JAK/STAT signaling pathway using phytocompounds for cancer prevention and therapy
Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …
Rutin (Bioflavonoid) as cell signaling pathway modulator: Prospects in treatment and chemoprevention
Cancer is a complex ailment orchestrated by numerous intrinsic and extrinsic pathways.
Recent research has displayed a deep interest in develo** plant-based cancer …
Recent research has displayed a deep interest in develo** plant-based cancer …
Therapeutical properties of apigenin: A review on the experimental evidence and basic mechanisms
ABSTRACT Apigenin (4,'5, 7-trihydroxyflavone) is one of the most studied flavonoids with
low toxicity and abundantly present phenolic compound in the plant kingdom. The main …
low toxicity and abundantly present phenolic compound in the plant kingdom. The main …
Apigenin role as cell-signaling pathways modulator: implications in cancer prevention and treatment
Cancer is a complex disease orchestrated by various extrinsic and intrinsic pathways. In
recent years, there has been a keen interest towards the development of natural extracts …
recent years, there has been a keen interest towards the development of natural extracts …
Role of STAT3 in the initiation, progression, proliferation and metastasis of breast cancer and strategies to deliver JAK and STAT3 inhibitors
Introduction Breast cancer (BC) accounts for the majority of cancers among the female
population. Anomalous activation of various signaling pathways has become an issue of …
population. Anomalous activation of various signaling pathways has become an issue of …
Coptisine from Coptis chinensis exerts diverse beneficial properties: A concise review
J Wu, Y Luo, D Deng, S Su, S Li, L **ang… - Journal of cellular …, 2019 - Wiley Online Library
Coptisine is a natural small‐molecular compound extracted from Coptis chinensis (CC) with
a history of using for thousands of years. This work aimed at summarizing coptisine's activity …
a history of using for thousands of years. This work aimed at summarizing coptisine's activity …
Targeting cancer with phytochemicals via their fine tuning of the cell survival signaling pathways
The role of phytochemicals as potential prodrugs or therapeutic substances against tumors
has come in the spotlight in the very recent years, thanks to the huge mass of encouraging …
has come in the spotlight in the very recent years, thanks to the huge mass of encouraging …
Natural compounds modulate the crosstalk between apoptosis-and autophagy-regulated signaling pathways: Controlling the uncontrolled expansion of tumor cells
C Braicu, O Zanoaga, AA Zimta, AB Tigu… - Seminars in Cancer …, 2022 - Elsevier
Due to the high number of annual cancer–related deaths, and the economic burden that this
malignancy affects today's society, the study of compounds isolated from natural sources …
malignancy affects today's society, the study of compounds isolated from natural sources …
[HTML][HTML] Nature-derived compounds modulating Wnt/β-catenin pathway: a preventive and therapeutic opportunity in neoplastic diseases
The Wnt/β-catenin signaling is a conserved pathway that has a crucial role in embryonic and
adult life. Dysregulation of the Wnt/β-catenin pathway has been associated with diseases …
adult life. Dysregulation of the Wnt/β-catenin pathway has been associated with diseases …