Concepts and methods of solid-state NMR spectroscopy applied to biomembranes

TR Molugu, S Lee, MF Brown - Chemical reviews, 2017 - ACS Publications
Concepts of solid-state NMR spectroscopy and applications to fluid membranes are
reviewed in this paper. Membrane lipids with 2H-labeled acyl chains or polar head groups …

Applications of NMR to membrane proteins

SJ Opella, FM Marassi - Archives of biochemistry and biophysics, 2017 - Elsevier
Membrane proteins present a challenge for structural biology. In this article, we review some
of the recent developments that advance the application of NMR to membrane proteins, with …

Solid‐state NMR spectroscopy on complex biomolecules

M Renault, A Cukkemane… - Angewandte Chemie …, 2010 - Wiley Online Library
Biomolecular applications of NMR spectroscopy are often merely associated with soluble
molecules or magnetic resonance imaging. However, since the late 1970s, solid‐state NMR …

Structures of the archaerhodopsin-3 transporter reveal that disordering of internal water networks underpins receptor sensitization

JF Bada Juarez, PJ Judge, S Adam, D Axford… - Nature …, 2021 - nature.com
Many transmembrane receptors have a desensitized state, in which they are unable to
respond to external stimuli. The family of microbial rhodopsin proteins includes one such …

Shedding new light on retinal protein photochemistry

A Wand, I Gdor, J Zhu, M Sheves… - Annual review of …, 2013 - annualreviews.org
The ultrafast spectroscopic investigation of novel retinal proteins challenges existing notions
concerning the course of primary events in these natural photoreceptors. We review two …

[PDF][PDF] Update 1 of: computational modeling approaches to structure–function analysis of G protein-coupled receptors

F Fanelli, PG De Benedetti - Chemical Reviews-Columbus, 2011 - researchgate.net
Any aspect of cell activity is regulated by extracellular signals that are recognized, decoded,
and transduced inside the cell via different classes of plasma membrane receptors. 1À3 G …

[HTML][HTML] Recent progress in the study of G protein-coupled receptors with molecular dynamics computer simulations

A Grossfield - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2011 - Elsevier
G protein-coupled receptors (GPCRs) are a large, biomedically important family of proteins,
and the recent explosion of new high-resolution structural information about them has …

Asymmetric toggling of a natural photoswitch: Ultrafast spectroscopy of Anabaena sensory rhodopsin

A Wand, R Rozin, T Eliash, KH Jung… - Journal of the …, 2011 - ACS Publications
Photochemistry in retinal proteins (RPs) is determined both by the properties of the retinal
chromophore and by its interactions with the surrounding protein. The initial retinal …

Solid-state NMR spectroscopy to study protein–lipid interactions

D Huster - Biochimica Et Biophysica Acta (BBA)-Molecular and …, 2014 - Elsevier
The appropriate lipid environment is crucial for the proper function of membrane proteins.
There is a tremendous variety of lipid molecules in the membrane and so far it is often …

Static solid-state 2H NMR methods in studies of protein side-chain dynamics

L Vugmeyster, D Ostrovsky - Progress in Nuclear Magnetic Resonance …, 2017 - Elsevier
In this review, we discuss the experimental static deuteron NMR techniques and
computational approaches most useful for the investigation of side-chain dynamics in …