Inflammation is a condition which contributes to a range of human diseases. It involves a
multitude of cell types, chemical mediators, and interactions. Eicosapentaenoic acid (EPA) …

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are n‐3 fatty acids found in
oily fish and fish oil supplements. These fatty acids are able to inhibit partly a number of …

Arachidonic acid (ARA, 20: 4 n-6) is an n-6 polyunsaturated 20-carbon fatty acid formed by
the biosynthesis from linoleic acid (LA, 18: 2 n-6). This review considers the essential role …

Numerous effects of n-3 fatty acids EPA and DHA on functional responses of cells involved
in inflammation and immunity have been described. Fatty acid-induced modifications in …

In this work we advance the hypothesis that omega-3 (ω-3) long-chain polyunsaturated fatty
acids (LCPUFAs) exhibit cytoprotective and cytotherapeutic actions contributing to a number …

In Westernized societies, average consumption of n-6 polyunsaturated fatty acids (PUFAs)
far exceeds nutritional requirements. The ratio of n-6 to n-3 PUFAs is generally> 10: 1 …

The fatty acid composition of inflammatory and immune cells is sensitive to change
according to the fatty acid composition of the diet. In particular, the proportion of different …

The immune system, including its inflammatory components, is fundamental to host defence
against pathogenic invaders. It is a complex system involving interactions amongst many …

Almost all nutrients in the diet play a crucial role in maintaining an “optimal” immune
response, such that deficient and excessive intakes can have negative consequences on …

Eukaryotic organisms as well as some prokaryotes and viruses contain sphingolipids, which
are defined by a common structural feature, ie, a “sphingoid base” backbone such as D …