In all organisms, the biotransformation of xenobiotics to less toxic and more hydrophilic
compounds represents an effective defense strategy. In pathogens, the biotransformation of …

Ticks are a large group of blood-feeding arthropods that transmit multiple human and animal
pathogens and are hence of importance to public health. The tick Haemaphysalis …

The goal of the present study was to assess the gene expression of xenobiotic metabolizing
enzymes (XMEs) Cytochrome P‐450 (CYP) and carboxylesterase (CE) related to …

Background Fasciola hepatica is the main agent of fasciolosis, a zoonotic disease affecting
livestock worldwide, and an emerging food-borne disease in humans. Even when effective …

Fasciola hepatica, commonly referred to as liver flukes, is a substantial zoonotic parasitic
disease of humans and livestock globally. While infection is readily controlled by …

Bioinformatics analysis of the complete transcriptome of Fasciola hepatica, identified a total
of ten putative carboxylesterase transcripts, including a 3146 bp mRNA transcript coding a …

The expression of the Fasciola hepatica carboxylesterase type B (CestB) gene is known to
be induced upon exposure to the anthelmintic triclabendazole (TCBZ), leading to a …

Fasciola hepatica anthelmintic resistance may be associated with the catalytic activity of
xenobiotic metabolizing enzymes. The gene expression of one of these enzymes, identified …

Parasitic zoonoses are diseases caused by parasites shared between animal hosts and
humans. Most of parasitic zoonoses are considered as neglected because of the absence of …

The expression of the Fasciola hepatica Carboxylesterase type B (CestB) gene is induced in
response to the anthelmintic triclabendazole (TCBZ), resulting in a significant increase in …