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Monitoring kinetic processes of drugs and metabolites: Surface-enhanced Raman spectroscopy
Monitoring the kinetic changes of drugs and metabolites plays a crucial role in fundamental
research, preclinical and clinical application. Raman spectroscopy (RS) is regarded as a …
research, preclinical and clinical application. Raman spectroscopy (RS) is regarded as a …
[HTML][HTML] Is Cryptococcus neoformans a pleomorphic fungus?
Highlights•Morphotypes are defined as transcriptionally distinct, stable, heritable growth
types.•Cryptococcus neoformans exhibits at least three morphotypes relevant to …
types.•Cryptococcus neoformans exhibits at least three morphotypes relevant to …
Recent Progress in Mushroom-Derived Ergothioneine: Techniques and Applications
Y Weng, M Zhu, H Ma, X Hu, L Ren - Food Bioscience, 2024 - Elsevier
Ergothioneine (EGT), a vital naturally occurring water-soluble sulfur-containing amino acid
and potent antioxidant, serves as one of the primary bioactive compounds found in …
and potent antioxidant, serves as one of the primary bioactive compounds found in …
Population heterogeneity in Cryptococcus neoformans: Impact on pathogenesis
Cryptococcus neoformans was first isolated from a patient in 1894 [1] and 130 years later, it
remains a prevalent global threat, especially for people living with human immunodeficiency …
remains a prevalent global threat, especially for people living with human immunodeficiency …
[HTML][HTML] Advancing cryptococcal treatment: The role of nanoparticles in mitigating antifungal resistance
Cryptococcus, a ubiquitous and formidable fungal pathogen, contributes to a substantial
global disease burden, with nearly 250,000 cases and 181,000 fatalities attributed to …
global disease burden, with nearly 250,000 cases and 181,000 fatalities attributed to …
Phenotypic heterogeneity in bacteria: the rise of antibiotic persistence, clinical implications, and therapeutic opportunities
The rising incidence of antimicrobial resistance (AMR) and the diminishing antibiotics
discovery pipeline have created an unprecedented scenario where minor infections could …
discovery pipeline have created an unprecedented scenario where minor infections could …
Penetration Profile of Terbinafine Compared to Amorolfine in Mycotic Human Toenails Quantified by Matrix-Assisted Laser Desorption Ionization–Fourier Transform …
N Joly-Tonetti, R Legouffe, A Tomezyk… - Infectious Diseases and …, 2024 - Springer
Introduction Amorolfine 5% lacquer is an established topical treatment for fungal infection of
the nails. The success of topical therapy for onychomycosis depends on whether the …
the nails. The success of topical therapy for onychomycosis depends on whether the …
Exploring emerging drug responses in Cryptococcus
Cryptococcosis imposes a considerable burden on public health, and emerging drug
responses to anticryptococcal drugs remain to be addressed. In this forum article we discuss …
responses to anticryptococcal drugs remain to be addressed. In this forum article we discuss …
[HTML][HTML] Targeted regulation of sterol biosynthesis genes according to perturbations in ergosterol biosynthesis in fungi
P Yu, M Zhou, D Yu, Z Zhang, S Ye, Y Yu, X Sun… - Journal of Advanced …, 2025 - Elsevier
Introduction The synthesis and regulation of ergosterol are vital for fungal growth and stress
adaptation. While ergosterol-mediated feedback regulation is a recognized mechanism …
adaptation. While ergosterol-mediated feedback regulation is a recognized mechanism …
The Antidepressant Sertraline Modulates Gene Expression and Alternative Splicing Events in the Dermatophyte Trichophyton rubrum: A Comprehensive Analysis
Background/Objectives: Dermatophytosis, a prevalent fungal infection of keratinized tissues,
is primarily caused by the filamentous fungus Trichophyton rubrum. Sertraline (SRT), an …
is primarily caused by the filamentous fungus Trichophyton rubrum. Sertraline (SRT), an …