[HTML][HTML] New insights into the diverse functions of the NR2F nuclear orphan receptor family

T Sa**ovic, G Baier - Frontiers in Bioscience-Landmark, 2023 - imrpress.com
Following gene expansion during evolution, today's phylogenetic tree of the NR2F family of
nuclear orphan receptors in mammals is represented by three different isoforms: NR2F1 …

Insights into the emerging immune checkpoint NR2F6 in cancer immunity

H Miftah, H Benthami, A Badou - Journal of Leukocyte Biology, 2024 - academic.oup.com
NR2F6 has emerged as a key player in immune regulation, especially in cancer immunity. It
has indeed been reported that NR2F6 could suppress the anti-tumor immune response, and …

Cerebrum, liver, and muscle regulatory networks uncover maternal nutrition effects in developmental programming of beef cattle during early pregnancy

WJS Diniz, MS Crouse, RA Cushman, KJ McLean… - Scientific reports, 2021 - nature.com
The molecular basis underlying fetal programming in response to maternal nutrition remains
unclear. Herein, we investigated the regulatory relationships between genes in fetal …

Chromatin accessibility and regulatory vocabulary across indicine cattle tissues

PA Alexandre, M Naval-Sánchez, M Menzies… - Genome biology, 2021 - Springer
Background Spatiotemporal changes in the chromatin accessibility landscape are essential
to cell differentiation, development, health, and disease. The quest of identifying regulatory …

Meta-analysis across Nellore cattle populations identifies common metabolic mechanisms that regulate feed efficiency-related traits

LFM Mota, SWB Santos, GAF Júnior, T Bresolin… - BMC genomics, 2022 - Springer
Background Feed efficiency (FE) related traits play a key role in the economy and
sustainability of beef cattle production systems. The accurate knowledge of the physiologic …

Biological network approach for the identification of regulatory long non-coding RNAs associated with metabolic efficiency in cattle

W Nolte, R Weikard, RM Brunner, E Albrecht… - Frontiers in …, 2019 - frontiersin.org
Background: Genomic regions associated with divergent livestock feed efficiency have been
found predominantly outside protein coding sequences. Long non-coding RNAs (lncRNA) …

Multi-breed genomic predictions and functional variants for fertility of tropical bulls

LR Porto-Neto, PA Alexandre, NJ Hudson, J Bertram… - PloS one, 2023 - journals.plos.org
Worldwide, most beef breeding herds are naturally mated. As such, the ability to identify and
select fertile bulls is critically important for both productivity and genetic improvement. Here …

[HTML][HTML] Gene co-expression in response to Staphylococcus aureus infection reveals networks of genes with specific functions during bovine subclinical mastitis

M Wang, N Bissonnette, M Laterrière… - Journal of Dairy …, 2023 - Elsevier
Staphylococcus aureus is one of the most prevalent contagious bacterial pathogen of bovine
mastitis. The subclinical mastitis it causes has long-term economic implications and it is …

Identification of predictor genes for feed efficiency in beef cattle by applying machine learning methods to multi-tissue transcriptome data

W Chen, PA Alexandre, G Ribeiro, H Fukumasu… - Frontiers in …, 2021 - frontiersin.org
Machine learning (ML) methods have shown promising results in identifying genes when
applied to large transcriptome datasets. However, no attempt has been made to compare …

Exploring the regulatory potential of long non-coding RNA in feed efficiency of indicine cattle

PA Alexandre, A Reverter, RB Berezin, LR Porto-Neto… - Genes, 2020 - mdpi.com
Long non-coding RNA (lncRNA) can regulate several aspects of gene expression, being
associated with complex phenotypes in humans and livestock species. In taurine beef cattle …