Spirocyclic scaffolds are incorporated in various approved drugs and drug candidates. The
increasing interest in less planar bioactive compounds has given rise to the development of …

Organosulfur compounds have long played a vital role in organic chemistry and in the
development of novel chemical structures and architectures. Prominent among these …

Electrochemistry, which employs electrons as reagents and avoids the use of traditional
redox reagents, becomes a powerful tool in oxidative dehydrogenation cross-coupling …

Complex molecular architectures containing cyclopropanes present significant challenges
for any synthetic chemist. This review aims to highlight the strategic considerations for …

Three-and four-membered rings, widespread motifs in nature and medicinal chemistry, have
fascinated chemists ever since their discovery. However, due to energetic considerations …

The effective use of ring strain has been applied to considerable advantage for the
construction of complex systems. The focus here is directed towards cyclopropanes as …

The construction of carbon− carbon bonds, along with the creation of stereogenic carbon
centers, continues to be an appealing and demanding area of research, and processes in …

Intermolecular cyclopropanation of mono-, di-, and trisubstituted olefins with α-bromo-β-
ketoesters and α-bromomalonates under organophotocatalysis is reported. The reaction …

A benchtop stable, bifunctional reagent for the redox-neutral cyclopropanation of olefins has
been developed. Triethylammonium bis (catecholato) iodomethylsilicate can be readily …

Since the dawn of the 20th century, the average life expectancy at birth has nearly doubled
due to advances in science and medicine. As medical records grew more reliable, it became …