This article reviews the behavioral neuroscience of extinction, the phenomenon in which a
behavior that has been acquired through Pavlovian or instrumental (operant) learning …

In human addicts, drug relapse and craving are often provoked by stress. Since 1995, this
clinical scenario has been studied using a rat model of stress-induced reinstatement of drug …

This paper reviews recent developments in the neurocircuitry and neurobiology of addiction
from a perspective of allostasis. A model is proposed for brain changes that occur during the …

High rates of relapse to drug use during abstinence is a defining feature of drug addiction. In
abstinent drug users, drug relapse is often precipitated by acute exposure to the self …

Rationale: The notion that stress leads to drug abuse in vulnerable individuals and relapse
in addicts is not new. Most major theories of addiction postulate that stress plays an …

This transdisciplinary review of the literature addresses the questions, Do stress and
negative affect (NA) promote smoking? and Does smoking genuinely relieve stress and NA …

Differential access to cocaine self-administration produced two patterns of drug intake in
rats. With 1 hour of access per session, drug intake remained low and stable. In contrast …

In our target article, we proposed that addiction could be envisioned as misperformance of a
decision-making machinery described by two systems (deliberative and habit systems) …

Tobacco addiction and chronic pain represent 2 highly prevalent and comorbid conditions
that engender substantial burdens upon individuals and systems. Interrelations between …

The objective of this article is to review data from studies that used a reinstatement model in
rats to elucidate the neural mechanisms underlying relapse to heroin and cocaine seeking …