Metagenomics has revolutionized microbiology by paving the way for a cultivation-
independent assessment and exploitation of microbial communities present in complex …

In nature microorganisms live in complex microbial communities. Comprehensive taxonomic
and functional knowledge about microbial communities supports medical and technical …

We are living through exciting times during which we are able to unravel the “microbial dark
matter” in and around us through the application of high‐resolution “meta‐omics” …

Abstract The northwestern Sargasso Sea undergoes annual cycles of productivity with
increased production in spring corresponding to periods of upwelling, and oligotrophy in …

Abstract We introduce Grinder (http://sourceforge. net/projects/biogrinder/), an open-source
bioinformatic tool to simulate amplicon and shotgun (genomic, metagenomic, transcriptomic …

Using proteins from soil or groundwater as functional biomarkers requires efficient
extraction. We developed an extraction method in which the separation of proteins from the …

In the postgenomic era, there is a clear recognition of the limitations of nucleic acid-based
methods for getting information on functions expressed by microbial communities in situ. In …

We know very little about the metabolic functioning and evolutionary dynamics of microbial
communities. Recent advances in comprehensive, sequencing-based methods, however …

Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry
(MS) is an emerging technique for microbial identification, characterization, and ty**. The …

The world of microorganisms comprises a vast diversity of live organisms, each with its
individual set of genes, cellular components and metabolic reactions that interact within the …