The steep rise of type 2 diabetes mellitus (T2DM) and associated complications go along
with mounting evidence of clinically important sex and gender differences. T2DM is more …

Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Estrogens have historically been associated with female reproduction, but work over the last
two decades established that estrogens and their main nuclear receptors (ESR1 and ESR2) …

Type 1 diabetes (T1D) is a multifactorial autoimmune disease driven by T-cells against the
insulin-producing islet β-cells, resulting in a marked loss of β-cell mass and function …

Bisphenol A (BPA) is one of the highest volume chemicals produced worldwide. This
compound is a building block of polycarbonate plastics often used for food and beverage …

Estrogens play a fundamental role in the physiology of the reproductive, cardiovascular,
skeletal, and central nervous systems. In this report, we review the literature in both rodents …

Background Increasing concern over bisphenol A (BPA) as an endocrine-disrupting
chemical and its possible effects on human health have prompted the removal of BPA from …

Synthetic chemicals currently used in a variety of industrial and agricultural applications are
leading to widespread contamination of the environment. Even though the intended uses of …

In 1991, a group of 21 scientists gathered at the Wingspread Conference Center to discuss
evidence of developmental alterations observed in wildlife populations after chemical …

Persistent organic pollutants (POPs) are lipophilic compounds that travel with lipids and
accumulate mainly in adipose tissue. Recent human evidence links low-dose POPs to an …