CACNA1C: association with psychiatric disorders, behavior, and neurogenesis
AL Moon, N Haan, LS Wilkinson… - Schizophrenia …, 2018 - academic.oup.com
Large-scale genome-wide association studies have consistently shown that genetic
variation in CACNA1C, a gene that encodes calcium voltage-gated channel subunit …
variation in CACNA1C, a gene that encodes calcium voltage-gated channel subunit …
CACNA1C (Cav1. 2) in the pathophysiology of psychiatric disease
S Bhat, DT Dao, CE Terrillion, M Arad, RJ Smith… - Progress in …, 2012 - Elsevier
One of the most consistent genetic findings to have emerged from bipolar disorder genome
wide association studies (GWAS) is with CACNA1C, a gene that codes for the α1C subunit …
wide association studies (GWAS) is with CACNA1C, a gene that codes for the α1C subunit …
MiR-137: an important player in neural development and neoplastic transformation
MicroRNAs (miRNAs) represent an important class of small regulatory RNAs that control
gene expression posttranscriptionally by targeting mRNAs for degradation or translation …
gene expression posttranscriptionally by targeting mRNAs for degradation or translation …
Genetic associations between voltage-gated calcium channels and psychiatric disorders
Psychiatric disorders are mental, behavioral or emotional disorders. These conditions are
prevalent, one in four adults suffer from any type of psychiatric disorders world-wide. It has …
prevalent, one in four adults suffer from any type of psychiatric disorders world-wide. It has …
The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function
SM Berger, D Bartsch - Cell and tissue research, 2014 - Springer
The use of specific activators and inhibitors that penetrate the central nervous system has
suggested an essential functional role of L-type calcium channels (LTCC) in several …
suggested an essential functional role of L-type calcium channels (LTCC) in several …
Monotherapy with major antihypertensive drug classes and risk of hospital admissions for mood disorders
Major depressive and bipolar disorders predispose to atherosclerosis, and there is accruing
data from animal model, epidemiological, and genomic studies that commonly used …
data from animal model, epidemiological, and genomic studies that commonly used …
Quantitative genetic research on sleep: a review of normal sleep, sleep disturbances and associated emotional, behavioural, and health-related difficulties
Over the past 50 years, well over 100 twin studies have focussed on understanding factors
contributing to variability in normal sleep–wake characteristics and sleep disturbances …
contributing to variability in normal sleep–wake characteristics and sleep disturbances …
Antihypertensive drugs and brain function: mechanisms underlying therapeutically beneficial and harmful neuropsychiatric effects
C Carnovale, C Perrotta, S Baldelli… - Cardiovascular …, 2023 - academic.oup.com
A bidirectional relationship exists between hypertension and psychiatric disorders, including
unipolar and bipolar depression, anxiety, post-traumatic stress disorder (PTSD), psychosis …
unipolar and bipolar depression, anxiety, post-traumatic stress disorder (PTSD), psychosis …
MIR137 gene and target gene CACNA1C of miR-137 contribute to schizophrenia susceptibility in Han Chinese
Recently, evidence has accumulated indicating that the MIR137 gene and the target gene
CACNA1C of miR-137 might be two of the most robustly implicated genes in schizophrenia …
CACNA1C of miR-137 might be two of the most robustly implicated genes in schizophrenia …
Association between bipolar spectrum features and treatment outcomes in outpatients with major depressive disorder
Objective: To assess the association between bipolar spectrum features and antidepressant
treatment outcome in MDD. Design: Open treatment followed by sequential randomized …
treatment outcome in MDD. Design: Open treatment followed by sequential randomized …