Growth Hormone-secreting adenomas exhibits variable biological behavior and
heterogeneous natural history, ranging from small adenomas and mild disease, to invasive …

Purposes Immunotherapies for solid tumor are gaining traction in the clinic, however, the
immunological landscape of pituitary adenomas (PAs) is not well defined. In the present …

Human growth hormone (GH) is the indispensable hormone for the maintenance of normal
physiological functions of the human body, including the growth, development, metabolism …

Aggressive somatotroph pituitary tumor that causes acromegaly is extremely rare and resists
conventional treatments such as multiple surgeries, radiotherapies, and various types of …

Pituitary tumors are a heterogeneous group of lesions (usually benign) and proper
understanding of the anatomy, physiology, and pathology of the hypothalamic/pituitary …

Background Nonfunctioning pituitary adenoma (NFPA) and growth hormone pituitary
adenoma (GHPA) are major subtypes of pituitary adenomas (PAs). The primary treatment is …

Aggressive growth hormone-secreting pituitary adenomas (GHPAs) represent an important
clinical problem in patients with acromegaly. Surgical therapy, although often the mainstay …

Purpose Patterns of extension of pituitary adenomas (PA) may vary according to PA subtype.
Understanding extrasellar extension patterns in growth hormone PAs (GHPA) vis-a-vis …

Acromegaly is a systemic disease that requires multidisciplinary treatment to achieve the
best clinical outcome. This study aimed to evaluate the outcomes of the endoscopic …

Patients with pituitary adenoma have often suffered cognitive impairment. The study aims to
identify the factors, and their impact, that affect the cognitive functions of pituitary adenoma …