Sepsis and septic shock are among the leading causes of death in intensive care units
worldwide. Numerous studies on their pathophysiology have revealed an imbalance in the …

Delirium is a neuropsychiatric syndrome characterized by a sudden and global impairment
in consciousness, attention and cognition. It is particularly frequent in elderly subjects with …

Background: Surgical procedures, including primary tumor resection, have been suggested
to suppress immune competence and to promote postoperative infections and cancer …

An 80‐year‐old man with multiple comorbidities presented to the emergency department
with tachypnea, tachycardia, fever, and critically low O2 saturation and definitive chest …

Introduction Vitamin D plays a key role in immune function. Deficiency may aggravate the
incidence and outcome of infectious complications in critically ill patients. We aimed to …

Objectives: Basic science and clinical studies suggest that sleep disturbance may be a
modifiable risk factor for postoperative delirium. We aimed to assess the association …

Sepsis is a life-threatening medical condition. Salidroside, a substance isolated from
Rhodiola rosea, possesses antioxidant and anti-inflammatory properties. The effect and …

Lactate significantly impacts immune cell function in sepsis and septic shock, transcending
its traditional view as just a metabolic byproduct. This review summarizes the role of lactate …

Ethnopharmacological relevance Xuebi**g injection (XBJ), a Chinese herbal medicine
containing extracts from 5 herbs, is frequently used as an add-on with standard therapies to …

Connexins and integrins, the two structurally and functionally distinct families of
transmembrane proteins, have been shown to be inter-connected by various modes of cross …