Applications of NMR for metabolomics and metabolic profiling continue to grow rapidly as
does the refinement of methods for the measurement, analysis, and interpretation of …

Corynebacterium glutamicum is the workhorse of biotechnological amino acid production.
For more than 50 years amino acid producing strains of this actinomycete have been …

Highlights•13 C-fluxomics provides quantification of metabolic activity in microorganisms.•
Increasing flux analysis capacity has the potential to accelerate strain design.•HT 13 C …

Background Succinate has been recognized as one of the most important bio-based
building block chemicals due to its numerous potential applications. However, efficient …

Anaerobic microbial metabolism drives critical functions within global ecosystems, host–
microbiota interactions, and industrial applications, yet remains ill-defined. Here we advance …

Background Cyanobacteria receive huge interest as green catalysts. While exploiting
energy from sunlight, they co-utilize sugar and CO2. This photomixotrophic mode enables …

Corynebacterium glutamicum, a model organism in microbial biotechnology, is known to
metabolize glucose under oxygen-deprived conditions to l-lactate, succinate, and acetate …

We previously reported on the impacts of the overexpression of individual genes of the
glycolytic pathway encoding glucokinase (GLK), glyceraldehyde phosphate dehydrogenase …

Performance losses during scale‐up are described since decades, but are still one of the
major obstacles for industrial bioprocess development. Consequently, robustness to …

Strain development is critical for microbial production of bio-based chemicals. The stereo-
complex form of polylactic acid, a complex of poly-l-and poly-d-lactic acid, is a promising …