The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …

There is a growing body of evidence to suggest that cannabinoids are beneficial for a range
of clinical conditions, including pain, inflammation, epilepsy, sleep disorders, the symptoms …

The term'endocannabinoid'—originally coined in the mid-1990s after the discovery of
membrane receptors for the psychoactive principle in Cannabis, Δ9-tetrahydrocannabinol …

The CB 1 and CB 2 cannabinoid receptors (CB 1 R, CB 2 R) are members of the G protein-
coupled receptor (GPCR) family that were identified over 20 years ago. CB 1 Rs and CB 2 …

Abstract Changes in synaptic efficacy are thought to be crucial to experience-dependent
modifications of neural function. The diversity of mechanisms underlying these changes is …

In the nineteenth century, marijuana was prescribed by physicians for maladies ranging from
eating disorders to rabies. However, as newer, more effective drugs were discovered and as …

This review focuses on the role of the peripheral nervous system in cutaneous biology and
disease. During the last few years, a modern concept of an interactive network between …

Non-alcoholic fatty liver disease is the clinical hepatic expression of metabolic syndrome.
The prevalence of non-alcoholic fatty liver disease is around 20–30%, and with a rapid …

Substance use disorder is characterized by repeated use of a substance, leading to
clinically significant distress, making it a serious public health concern. The …

The use of recreational drugs of abuse has generated serious health concerns. There is a
long-recognized relationship between addictive drugs and increased levels of infections …