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[HTML][HTML] Enzymes for detoxification of various mycotoxins: origins and mechanisms of catalytic action
I Lyagin, E Efremenko - Molecules, 2019 - mdpi.com
Mycotoxins are highly dangerous natural compounds produced by various fungi. Enzymatic
transformation seems to be the most promising method for detoxification of mycotoxins. This …
transformation seems to be the most promising method for detoxification of mycotoxins. This …
Bioenzymatic detoxification of mycotoxins
M Liu, X Zhang, H Luan, Y Zhang, W Xu… - Frontiers in …, 2024 - frontiersin.org
Mycotoxins are secondary metabolites produced during the growth, storage, and
transportation of crops contaminated by fungi and are physiologically toxic to humans and …
transportation of crops contaminated by fungi and are physiologically toxic to humans and …
[HTML][HTML] Turning inside out: Filamentous fungal secretion and its applications in biotechnology, agriculture, and the clinic
Filamentous fungi are found in virtually every marine and terrestrial habitat. Vital to this
success is their ability to secrete a diverse range of molecules, including hydrolytic enzymes …
success is their ability to secrete a diverse range of molecules, including hydrolytic enzymes …
Aspergillus fumigatus mitogen-activated protein kinase MpkA is involved in gliotoxin production and self-protection
P Alves de Castro, C Figueiredo Pinzan… - Nature …, 2024 - nature.com
Aspergillus fumigatus is a saprophytic fungus that can cause a variety of human diseases
known as aspergillosis. Mycotoxin gliotoxin (GT) production is important for its virulence and …
known as aspergillosis. Mycotoxin gliotoxin (GT) production is important for its virulence and …
The toxic mechanism of gliotoxins and biosynthetic strategies for toxicity prevention
W Ye, T Liu, W Zhang, W Zhang - International Journal of Molecular …, 2021 - mdpi.com
Gliotoxin is a kind of epipolythiodioxopiperazine derived from different fungi that is
characterized by a disulfide bridge. Gliotoxins can be biosynthesized by a gli gene cluster …
characterized by a disulfide bridge. Gliotoxins can be biosynthesized by a gli gene cluster …
Epipolythiodioxopiperazine‐Based Natural Products: Building Blocks, Biosynthesis and Biological Activities
EM Huber - ChemBioChem, 2022 - Wiley Online Library
Epipolythiodioxopiperazines (ETPs) are fungal secondary metabolites that share a 2, 5‐
diketopiperazine scaffold built from two amino acids and bridged by a sulfide moiety …
diketopiperazine scaffold built from two amino acids and bridged by a sulfide moiety …
One-pot assay using a target-driven split aptamer recognition and assembly strategy for convenient and rapid detection of gliotoxin
X Zheng, Z Hu, S Gao, Z Li, J Chen, G Zhang, N Kong… - Food Chemistry, 2024 - Elsevier
An aptamer targeting gliotoxin (GTX) was optimized to increase the binding affinity by
approximately 20 times and achieve higher structural stability and targeting specificity …
approximately 20 times and achieve higher structural stability and targeting specificity …
Target-induced AIE effect coupled with CRISPR/Cas12a system dual-signal biosensing for the ultrasensitive detection of Gliotoxin
X Ma, Y Zhang, X Qiao, Y Yuan, Q Sheng… - Analytical …, 2023 - ACS Publications
Here, a novel rapid and ultrasensitive aptamer biosensor was designed for target-induced
activation of AIE effect and followed by the activation of Crispr Cas12a (LbCpf1)-mediated …
activation of AIE effect and followed by the activation of Crispr Cas12a (LbCpf1)-mediated …
Involvement of Sulfur in the Biosynthesis of Essential Metabolites in Pathogenic Fungi of Animals, Particularly Aspergillus spp.: Molecular and Therapeutic …
AM Traynor, KJ Sheridan, GW Jones… - Frontiers in …, 2019 - frontiersin.org
Fungal sulfur uptake is required for incorporation into the sidechains of the amino acids
cysteine and methionine, and is also essential for the biosynthesis of the antioxidant …
cysteine and methionine, and is also essential for the biosynthesis of the antioxidant …
Production, stability and degradation of Trichoderma gliotoxin in growth medium, irrigation water and agricultural soil
Gliotoxin produced by Trichoderma virens is inhibitory against various phytopathogenic
fungi and bacteria. However, its stability in soil-ecosystem has not yet been well-defined …
fungi and bacteria. However, its stability in soil-ecosystem has not yet been well-defined …