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New opportunities and old challenges in the clinical translation of nanotheranostics
Nanoparticle-based systems imbued with both diagnostic and therapeutic functions, known
as nanotheranostics, have enabled remarkable progress in guiding focal therapy, inducing …
as nanotheranostics, have enabled remarkable progress in guiding focal therapy, inducing …
Marshalling the potential of Auger electron radiopharmaceutical therapy
Auger electron (AE) radiopharmaceutical therapy (RPT) may have the same therapeutic
efficacy as α-particles for oncologic small disease, with lower risks of normal-tissue toxicity …
efficacy as α-particles for oncologic small disease, with lower risks of normal-tissue toxicity …
Applications of radiocomplexes with thiosemicarbazones and bis (thiosemicarbazones) in diagnostic and therapeutic nuclear medicine
Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …
[HTML][HTML] The chemical scaffold of theranostic radiopharmaceuticals: radionuclide, bifunctional chelator, and pharmacokinetics modifying linker
Therapeutic radiopharmaceuticals have been researched extensively in the last decade as
a result of the growing research interest in personalized medicine to improve diagnostic …
a result of the growing research interest in personalized medicine to improve diagnostic …
[HTML][HTML] Radiometals in imaging and therapy: highlighting two decades of research
The present article highlights the important progress made in the last two decades in the
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …
Organic coordination nanoparticles for phototheranostics
Nanomedicines can integrate multiple functionalities to improve the efficacy of disease
treatment with reduced off-target toxicity. However, challenges such as tedious synthesis …
treatment with reduced off-target toxicity. However, challenges such as tedious synthesis …
Evaluation of 134Ce/134La as a PET imaging theranostic pair for 225Ac α-radiotherapeutics
225Ac-targeted α-radiotherapy is a promising approach to treating malignancies, including
prostate cancer. However, α-emitting isotopes are difficult to image because of low …
prostate cancer. However, α-emitting isotopes are difficult to image because of low …
Radioimmunotherapy in oncology: overview of the last decade clinical trials
Simple Summary Monoclonal antibody-bearing radionuclides have been under clinical
investigation over the last two decades for their use in theranostic (diagnostic and …
investigation over the last two decades for their use in theranostic (diagnostic and …
An Overview of In Vitro Assays of 64Cu-, 68Ga-, 125I-, and 99mTc-Labelled Radiopharmaceuticals Using Radiometric Counters in the Era of Radiotheranostics
Radionuclides are unstable isotopes that mainly emit alpha (α), beta (β) or gamma (γ)
radiation through radiation decay. Therefore, they are used in the biomedical field to label …
radiation through radiation decay. Therefore, they are used in the biomedical field to label …
Bispidine chelators for radiopharmaceutical applications with lanthanide, actinide, and main group metal ions
I Kopp, P Cieslik, K Anger, T Josephy… - Inorganic …, 2023 - ACS Publications
Octadentate and specifically nonadentate ligands with a bispidine scaffold (3, 7-diazabicyclo
[3.3. 1] nonane) are known to be efficiently coordinated to a range of metal ions of interest in …
[3.3. 1] nonane) are known to be efficiently coordinated to a range of metal ions of interest in …