Here we tell the story of ivermectin, describing its anthelmintic and insecticidal actions and
recent studies that have sought to reposition ivermectin for the treatment of other diseases …

Anthelmintic resistance is a significant threat to livestock production systems worldwide and
is emerging as an important issue in companion animal parasite management. It is also an …

Like other pathogens, parasitic helminths can rapidly evolve resistance to drug treatment.
Understanding the genetic basis of anthelmintic drug resistance in parasitic nematodes is …

Haemonchus contortus is a globally distributed and economically important gastrointestinal
pathogen of small ruminants and has become a key nematode model for studying …

Sheep farming is the backbone of a rural economy in develo** countries, and
haemonchosis is a major impediment in the way of its progress. Haemonchus contortus (H …

Host-parasite interactions exert strong selection pressures on the genomes of both host and
parasite. These interactions can lead to negative frequency-dependent selection, a form of …

Nematodes are important parasites of people and animals, and in natural ecosystems they
are a major ecological force. Strongyloides ratti is a common parasitic nematode of wild rats …

The antiparasitic drug ivermectin plays an essential role in human and animal health
globally. However, ivermectin resistance is widespread in veterinary helminths and there are …

Strongyloidiasis represents a major medical and veterinary helminthic disease. Human
infection is caused by Strongyloides stercoralis, Strongyloides fuelleborni fuelleborni and …

Anthelmintic drugs are the major line of defense against parasitic nematode infections, but
the arsenal is limited and resistance threatens sustained efficacy of the available drugs …