1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

In the field of C–H bond functionalization chemistry, directed C–H bond activation strategies
are highly appreciated due to the high efficiency and selectivity of such reactions towards a …

The arylethylamine pharmacophore is conserved across a range of biologically active
natural products and pharmaceuticals, particularly in molecules that act on the central …

Vicinal alkene carboamination is a highly efficient and practical synthetic strategy for the
straightforward preparation of diverse and valuable amine derivatives starting from simple …

The concurrent installation of C–C and C–N bonds across alkene frameworks represents a
powerful tool to prepare motifs that are ubiquitous in pharmaceuticals and bioactive …

Visual kinetic analyses extract meaningful mechanistic information from experimental data
using the naked-eye comparison of appropriately modified progress reaction profiles. Basic …

Two-or one-electron-mediated difunctionalizations of internal alkenes represent
straightforward approaches to assemble molecular complexity by the simultaneous …

Alkene aminoarylation with a single, bifunctional reagent is a concise synthetic strategy. We
report a catalytic protocol for the addition of arylsulfonylacetamides across electron-rich …

Three‐component reactions can directly convert three reactants into the desired products in
one pot and thus greatly shorten the synthetic path. Recently, transition‐metal catalysis has …

Alkene hydrocarbonation reactions have been developed to supplement traditional
electrophile-nucleophile cross-coupling reactions. The branch-selective hydroalkylation …