The rapid pace of disease gene discovery has resulted in tremendous advances in the field
of epilepsy genetics. Clinical testing with comprehensive gene panels, exomes, and …

Nowadays a substantial armamentarium of antiepileptic drugs (AEDs) is available, including
drugs with different mechanisms of action, pharmacokinetics, efficacy and tolerability; …

Temporal lobe epilepsy is the commonest partial epilepsy of adulthood. Although generally
perceived as an acquired disorder, several forms of familial temporal lobe epilepsy, with …

Objective Familial mesial temporal lobe epilepsy (FMTLE) is an important focal epilepsy
syndrome; its molecular genetic basis is unknown. Clinical descriptions of FMTLE vary …

Atlas of EEG, Seizure Semiology, and Management is a comprehensive yet concise
textbook with a focus on practical use of EEG and clinical neurology in the diagnosis and …

Objective To describe the clinical phenotype of 7 families with Autosomal Dominant Lateral
Temporal Lobe Epilepsy (ADLTE) related to Reelin (RELN) mutations comparing the data …

Introduction The differentiation between focal and generalized epilepsies based on clinical
and electroencephalographic features is difficult and sometimes confusing. Objective To …

To contribute to the identification of brain regions involved in déjà-vu, we studied the
metabolic pattern of cortical involvement in patients with seizures of temporal lobe origin …

Mutations in the DEPDC 5 (DEP domain–containing protein 5) gene are a major cause of
familial focal epilepsy with variable foci (FFEVF) and are predicted to account for 12–37% of …

Objective The cause of mesial temporal lobe epilepsy (MTLE) is often unknown. We
ascertained to what extent newly diagnosed nonlesional MTLE actually represents familial …