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SARS-CoV-2 variant biology: immune escape, transmission and fitness
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
The emergence of SARS-CoV-2 Omicron subvariants: current situation and future trends
SUMMARY The SARS-CoV-2 Omicron variant (B. 1.1. 529) has been the most recent variant
of concern (VOC) established by the World Health Organization (WHO). Because of its …
of concern (VOC) established by the World Health Organization (WHO). Because of its …
The altered entry pathway and antigenic distance of the SARS-CoV-2 Omicron variant map to separate domains of spike protein
TP Peacock, JC Brown, J Zhou, N Thakur, K Sukhova… - biorxiv, 2022 - biorxiv.org
At the end of 2021 a new SARS-CoV-2 variant, Omicron, emerged and quickly spread
across the world. It has been demonstrated that Omicron's high number of Spike mutations …
across the world. It has been demonstrated that Omicron's high number of Spike mutations …
Heterogeneous infectivity and pathogenesis of SARS-CoV-2 variants beta, delta and omicron in transgenic K18-hACE2 and wildtype mice
F Tarrés-Freixas, B Trinité, A Pons-Grífols… - Frontiers in …, 2022 - frontiersin.org
The emerging SARS-CoV-2 variants of concern (VOCs) may display enhanced
transmissibility, more severity and/or immune evasion; however, the pathogenesis of these …
transmissibility, more severity and/or immune evasion; however, the pathogenesis of these …
[HTML][HTML] Rapid escape of new SARS-CoV-2 Omicron variants from BA. 2-directed antibody responses
Summary In November 2021, Omicron BA. 1, containing a raft of new spike mutations,
emerged and quickly spread globally. Intense selection pressure to escape the antibody …
emerged and quickly spread globally. Intense selection pressure to escape the antibody …
Double-antibody-based nano-biosensing system for the onsite monitoring of SARS-CoV-2 variants
The fast and reliable diagnosis of COVID-19 is the foremost priority for promoting public
health interventions. Therefore, double-antibody-based immunobiosensor chips were …
health interventions. Therefore, double-antibody-based immunobiosensor chips were …
SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice
The COVID-19 pandemic has been fueled by SARS-CoV-2 novel variants of concern (VOC)
that have increased transmissibility, receptor binding affinity, and other properties that …
that have increased transmissibility, receptor binding affinity, and other properties that …
Effectiveness of VSV vectored SARS-CoV-2 spike when administered through intranasal, intramuscular or a combination of both
S Beitari, G Agbayani, M Hewitt, D Duque… - Scientific Reports, 2023 - nature.com
A critical feature of the VSV vector platform is the ability to pseudotype the virus with different
glycoproteins from other viruses, thus altering cellular tropism of the recombinant virus. The …
glycoproteins from other viruses, thus altering cellular tropism of the recombinant virus. The …
Experimental co-infection of calves with SARS-CoV-2 Delta and Omicron variants of concern
K Cool, NN Gaudreault, JD Trujillo… - Emerging Microbes & …, 2024 - Taylor & Francis
Since emerging in late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has repeatedly crossed the species barrier with natural infections reported in various …
2) has repeatedly crossed the species barrier with natural infections reported in various …
The SARS-CoV-2 Alpha variant exhibits comparable fitness to the D614G strain in a Syrian hamster model
Abstract Late 2020, SARS-CoV-2 Alpha variant emerged in United Kingdom and gradually
replaced G614 strains initially involved in the global spread of the pandemic. In this study …
replaced G614 strains initially involved in the global spread of the pandemic. In this study …