Feeding, which is essential for all animals, is regulated by homeostatic mechanisms. In
addition, food consumption is temporally coordinated by the brain over the circadian (~ 24 h) …

Dietary restriction (DR) decreases body weight, improves health, and extends lifespan. DR
can be achieved by controlling how much and/or when food is provided, as well as by …

Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …

The circadian timing system governs daily biological rhythms, synchronising physiology and
behaviour to the temporal world. External time cues, including the light‐dark cycle and …

During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

Many molecular, physiological and behavioural processes display distinct 24-hour rhythms
that are directed by the circadian system. The master clock, located in the suprachiasmatic …

The mammalian brain is composed of thousands of interacting neural cell types. Systematic
approaches to establish the molecular identity of functional populations of neurons would …

Circadian clocks maintain periodicity in internal cycles of behavior, physiology, and
metabolism, enabling organisms to anticipate the 24-h rotation of the Earth. In mammals …

Ultradian (∼ 4 hr) rhythms in locomotor activity that do not depend on the master circadian
pacemaker in the suprachiasmatic nucleus have been observed across mammalian …

Starved animals often exhibit elevated locomotion, which has been speculated to partly
resemble foraging behavior and facilitate food acquisition and energy intake. Despite its …